| Gene Symbol |
PANK1
|
| Entrez Gene |
53354
|
| Alt Symbol |
PANK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pantothenate kinase 1
|
| Other Description |
pantothenic acid kinase 1
|
| Swissprots |
Q8TBQ8 A6NIP0 Q8TE04 Q7Z495 Q7RTX6
|
| Accessions |
EAW50130 EAW50131 EAW50132 EAW50133 Q8TE04 AF355198 AAL86371 AK057932 AK125428 BAG54195 AK127777 BAG54569 AY027661 AAK20916 AY027662 AAK20917 AY027663 AAK20918 BC026296 AAH26296 BC036934 BC156381 AAI56382 BC172476 AAI72476 BK000008 DAA00002 BK000009 DAA00003 XM_005269902 XP_005269959 NM_138316 NP_612189 NM_148977 NP_683878 NM_148978 NP_683879
|
| Function |
Plays a role in the physiological regulation of the intracellular CoA concentration. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:14523052}.
|
| Tissue Specificity |
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. {ECO:0000269|PubMed:14523052}.
|
| Top Pathways |
Pantothenate and CoA biosynthesis
|