Gene Symbol | PANK1 |
---|---|
Entrez Gene | 53354 |
Alt Symbol | PANK |
Species | Human |
Gene Type | protein-coding |
Description | pantothenate kinase 1 |
Other Description | pantothenic acid kinase 1 |
Swissprots | Q8TBQ8 A6NIP0 Q8TE04 Q7Z495 Q7RTX6 |
Accessions | EAW50130 EAW50131 EAW50132 EAW50133 Q8TE04 AF355198 AAL86371 AK057932 AK125428 BAG54195 AK127777 BAG54569 AY027661 AAK20916 AY027662 AAK20917 AY027663 AAK20918 BC026296 AAH26296 BC036934 BC156381 AAI56382 BC172476 AAI72476 BK000008 DAA00002 BK000009 DAA00003 XM_005269902 XP_005269959 NM_138316 NP_612189 NM_148977 NP_683878 NM_148978 NP_683879 |
Function | Plays a role in the physiological regulation of the intracellular CoA concentration. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14523052}. |
Tissue Specificity | Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. {ECO:0000269|PubMed:14523052}. |
Top Pathways | Pantothenate and CoA biosynthesis |
PANK1 CRISPR/Cas9 KO Plasmid (h) - sc-408890 from Santa Cruz Biotechnology
|
||||||||
PANK1 HDR Plasmid (h) - sc-408890-HDR from Santa Cruz Biotechnology
|
||||||||
PANK1 Double Nickase Plasmid (h) - sc-408890-NIC from Santa Cruz Biotechnology
|
||||||||
PANK1 Double Nickase Plasmid (h2) - sc-408890-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PANK1 CRISPR Activation Plasmid (h) - sc-408890-ACT from Santa Cruz Biotechnology
|
||||||||
PANK1 CRISPR Activation Plasmid (h2) - sc-408890-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PANK1 Lentiviral Activation Particles (h) - sc-408890-LAC from Santa Cruz Biotechnology
|
||||||||
PANK1 Lentiviral Activation Particles (h2) - sc-408890-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PANK1 siRNA (h) - sc-76040 from Santa Cruz Biotechnology
|
||||||||
PANK1 shRNA Plasmid (h) - sc-76040-SH from Santa Cruz Biotechnology
|
||||||||
PANK1 shRNA (h) Lentiviral Particles - sc-76040-V from Santa Cruz Biotechnology
|
||||||||
PANK1 RNAi - H00053354-R06 from Novus Biologicals
|
||||||||
PANK1 RNAi - H00053354-R04 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU158711 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1513 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1512 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1510 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1511 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1508 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1509 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN16303 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16303 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09410 from Sigma-Aldrich
|
||||||||
PANK1 siRNA (Human) - CRH9968 from Cohesion Biosciences
|
||||||||
PANK1 RNAi - H00053354-R05 from Novus Biologicals
|