SLC4A7

Gene Symbol SLC4A7
Entrez Gene 9497
Alt Symbol NBC2, NBC3, NBCN1, SBC2, SLC4A6
Species Human
Gene Type protein-coding
Description solute carrier family 4, sodium bicarbonate cotransporter, member 7
Other Description bicarbonate transporter|electroneutral Na/HCO(3) cotransporter|sodium bicarbonate cotransporter 2|sodium bicarbonate cotransporter 2b|sodium bicarbonate cotransporter 3|solute carrier family 4 member 7
Swissprots B6DY53 B5M451 Q9HC88 O60350 B5M449 B2CI53 Q9UIB9 Q6AHZ9 A6NIA8 C9JST9 D3K175 B5M453 B6DY52 D3K174 Q9Y6M7 B5M452
Accessions EAW64381 EAW64382 EAW64383 EAW64384 Q9Y6M7 AA569234 AB012130 BAA25898 AF047033 AAD38322 AF053755 AAF21720 AF089726 AAG16773 AK309734 AK310865 AL389947 AL833589 BC156213 AAI56214 BC172463 AAI72463 CR627428 CAH10515 DA756057 EU499349 ACB47400 EU934246 ACH61958 EU934247 ACH61959 EU934248 ACH61960 EU934249 ACH61961 EU934250 ACH61962 FJ178574 ACI24740 FJ178575 ACI24741 FJ178576 ACI24742 GU354307 ADC32649 GU354308 ADC32650 GU354309 ADC32651 GU354310 ADC32652 XM_005265598 XP_005265655 XM_005265600 XP_005265657 XM_005265601 XP_005265658 XM_006713421 XP_006713484 XM_011534255 XP_011532557 XM_011534256 XP_011532558 XM_011534257 XP_011532559 XM_011534258 XP_011532560 XM_011534259 XP_011532561 XM_011534260 XP_011532562 XM_011534261 XP_011532563 XM_011534262 XP_011532564 XM_011534263 XP_011532565 XM_011534264 XP_011532566 XM_011534265 XP_011532567 XR_940517 XR_940518 XR_940519 NM_001258379 NP_001245308 NM_001258380 NP_001245309 NM_003615 NP_003606
Function Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity. {ECO:0000269|PubMed:10347222, ECO:0000269|PubMed:12403779}.
Subcellular Location Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, stereocilium {ECO:0000250}. Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. Isoform 1 is expressed in skeletal muscle and heart muscle. {ECO:0000269|PubMed:9610397}.

SLC4A7 (L-15) - sc-99633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

SLC4A7 (F-15) - sc-99632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 antibody - ab82335 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of SLC4A7 staining in human normal kidney formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab82335, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-SLC4A7 antibody - ab89656 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (C-Terminus) - LS-C37469 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (C-Terminus) - LS-C37470 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (Internal) - LS-C153553 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (Internal) - LS-C145070 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, APC) - LS-C224096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, Biotin) - LS-C224097 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, FITC) - LS-C224098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, PE) - LS-C224099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, Azide-free, HRP) - LS-C224100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214, AP) - LS-C227080 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1193-1222) - LS-C325174 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC4A7 Antibody (aa1186-1214) - LS-C161257 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SLC4A7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human spleen tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

SLC4A7/Sodium bicarbonate cotransporter 3 Antibody - NBP1-30015 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

SLC4A7/Sodium bicarbonate cotransporter 3 Antibody - NBP1-87850 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SLC4A7/Sodium bicarbonate cotransporter 3 Antibody [NBP1-87850] - Staining of human small intestine shows strong cytoplasmic membranous positivity in glandular cells.

Slc4a7/Nbcn1 Polyclonal Antibody - bs-1530R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti SLC4A7/NBCN1 Polyclonal Antibody, Unconjugated (bs-1530R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

ANTI-SLC4A7 (C-TERM) antibody produced in rabbit - SAB1303592 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC4A7 Antibody - C-terminal region (OAAB03064) - OAAB03064 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SLC4A7-Antibody-C-term - AP5655b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SLC4A7 Antibody (C-term) (Cat. #AP5655b) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the SLC4A7 antibody detected the SLC4A7 protein (arrow).

Slc4a7/Nbcn1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-1530R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc4a7/Nbcn1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-1530R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc4a7/Nbcn1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-1530R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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