Gene Symbol | ATP8B2 |
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Entrez Gene | 57198 |
Alt Symbol | ATPID |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
Other Description | ATPase, class I, type 8B, member 2|P4-ATPase flippase complex alpha subunit ATP8B2|phospholipid-transporting ATPase ID|probable phospholipid-transporting ATPase ID |
Swissprots | B4E3P4 Q96I43 Q6NT69 P98198 Q7Z486 Q96NQ7 |
Accessions | EAW53204 EAW53205 EAW53206 EAW53207 EAW53208 P98198 AB032963 BAA86451 AI857468 AK054886 BAB70822 AK304806 BAG65556 AL137537 CAB70799 AY302537 AAQ19027 BC007837 AAH07837 BC030288 AAH30288 BC041573 BC063858 AAH63858 BC069264 AAH69264 BC140441 AAI40442 DQ576212 X58235 CAA41193 XM_005245355 XP_005245412 XM_005245356 XP_005245413 XR_921901 NM_001005855 NP_001005855 NM_020452 NP_065185 |
Function | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). {ECO:0000305}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein. Cell membrane. Note=TMEM30A, but not TMEM30B, is required for its export from ER to the plasma membrane. |
Tissue Specificity | Isoform 3 is ubiquitous, with highest expression in aorta, cerebellum and uterus. {ECO:0000269|PubMed:12880872}. |
Human ATP8B2 protein fragment - ab163523 from Abcam
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ATP8B2 Antibody Blocking Peptide - LS-E490 from LifeSpan Bioscience
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ATP8B2 Antibody Blocking Peptide - LS-E16358 from LifeSpan Bioscience
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ATP8B2 Antibody Blocking Peptide - LS-E16359 from LifeSpan Bioscience
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ATP8B2 Partial Recombinant Protein - H00057198-Q01 from Novus Biologicals
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AT8B2-Antibody-N-term-Blocking-peptide - BP10779a from Abgent, a WuXi AppTec company
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ATP8B2 Blocking Peptide - 33R-4690 from Fitzgerald
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ATP8B2 Blocking Peptide - 33R-5795 from Fitzgerald
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ATP8B2 - H00057198-Q01-10 from Acris Antibodies
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ATP8B2 - H00057198-Q01-25 from Acris Antibodies
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ATP8B2 fusion protein - ag19018 from Proteintech Group
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ATP8B2 fusion protein - ag19015 from Proteintech Group
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ATP8B2 (transcript variant 2) - TP315926 from Acris Antibodies
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Probable phospholipid-transporting ATPase ID (ATP8B2), partial, Recombinant Protein - MBS957194 from MyBioSource
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ATP8B2 Recombinant Protein Antigen - NBP2-30486PEP from Novus Biologicals
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ATP8B2 Peptide, Human - M34GP01201H from Creative Peptides
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