Gene Symbol | ATP8B2 |
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Entrez Gene | 57198 |
Alt Symbol | ATPID |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
Other Description | ATPase, class I, type 8B, member 2|P4-ATPase flippase complex alpha subunit ATP8B2|phospholipid-transporting ATPase ID|probable phospholipid-transporting ATPase ID |
Swissprots | B4E3P4 Q96I43 Q6NT69 P98198 Q7Z486 Q96NQ7 |
Accessions | EAW53204 EAW53205 EAW53206 EAW53207 EAW53208 P98198 AB032963 BAA86451 AI857468 AK054886 BAB70822 AK304806 BAG65556 AL137537 CAB70799 AY302537 AAQ19027 BC007837 AAH07837 BC030288 AAH30288 BC041573 BC063858 AAH63858 BC069264 AAH69264 BC140441 AAI40442 DQ576212 X58235 CAA41193 XM_005245355 XP_005245412 XM_005245356 XP_005245413 XR_921901 NM_001005855 NP_001005855 NM_020452 NP_065185 |
Function | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). {ECO:0000305}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein. Cell membrane. Note=TMEM30A, but not TMEM30B, is required for its export from ER to the plasma membrane. |
Tissue Specificity | Isoform 3 is ubiquitous, with highest expression in aorta, cerebellum and uterus. {ECO:0000269|PubMed:12880872}. |
ATP8B2 (D-16) - sc-249995 from Santa Cruz Biotechnology
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ATP8B2 (E-16) - sc-249994 from Santa Cruz Biotechnology
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Anti-ATP8B2 antibody - ab187992 from Abcam
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Anti-ATP8B2 antibody - ab104336 from Abcam
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Anti-ATP8B2 antibody - ab104337 from Abcam
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Anti-ATP8B2 Antibody (aa21-51, AP) - LS-C232918 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51, APC) - LS-C232920 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (N-Terminus) - LS-C116270 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51, Biotin) - LS-C232921 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51, FITC) - LS-C232922 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa35-84) - LS-C116271 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51, PE) - LS-C232923 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51, Azide-free, HRP) - LS-C249475 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51) - LS-C156557 from LifeSpan Bioscience
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Anti-ATP8B2 Antibody (aa21-51) - LS-C319647 from LifeSpan Bioscience
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ATP8B2 Antibody - NBP1-57019 from Novus Biologicals
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ATP8B2 Antibody - NBP1-57018 from Novus Biologicals
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ATP8B2 Antibody - NBP2-30486 from Novus Biologicals
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Anti-ATP8B2, (N-terminal) antibody produced in rabbit - SAB2105589 from Sigma-Aldrich
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ANTI-AT8B2 (N-TERMINAL) antibody produced in rabbit - SAB1306098 from Sigma-Aldrich
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ATP8B2 antibody - N-terminal region (ARP44521_P050) - ARP44521_P050 from Aviva Systems Biology
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ATP8B2 antibody - N-terminal region (ARP44522_P050) - ARP44522_P050 from Aviva Systems Biology
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ATP8B2 Antibody - N-terminal region (OAAB00795) - OAAB00795 from Aviva Systems Biology
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AT8B2-Antibody-N-term - AP10779a from Abgent, a WuXi AppTec company
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ATP8B2 antibody, N-term - GTX46694 from GeneTex
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