Gene Symbol |
Mtr
|
Entrez Gene |
81522
|
Alt Symbol |
methioninesynthase
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
5-methyltetrahydrofolate-homocysteine methyltransferase
|
Other Description |
5-methyltetrahydrofolate--homocysteine methyltransferase|MS|methionine synthase|vitamin-B12 dependent methionine synthase
|
Swissprots |
Q9Z2Q4
|
Accessions |
EDM06980 EDM06981 Q9Z2Q4 AF034214 AAD05384 NM_030864 NP_110491
|
Function |
Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Top Pathways |
Cysteine and methionine metabolism, Selenocompound metabolism, Biosynthesis of amino acids, One carbon pool by folate
|