Gene Symbol | Mtr |
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Entrez Gene | 81522 |
Alt Symbol | methioninesynthase |
Species | Rat |
Gene Type | protein-coding |
Description | 5-methyltetrahydrofolate-homocysteine methyltransferase |
Other Description | 5-methyltetrahydrofolate--homocysteine methyltransferase|MS|methionine synthase|vitamin-B12 dependent methionine synthase |
Swissprots | Q9Z2Q4 |
Accessions | EDM06980 EDM06981 Q9Z2Q4 AF034214 AAD05384 NM_030864 NP_110491 |
Function | Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | Cysteine and methionine metabolism, Selenocompound metabolism, Biosynthesis of amino acids, One carbon pool by folate |
CompoZr® Knockout ZFN Kit - CKOZFN57597 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND57597 from Sigma-Aldrich
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MTR siRNA (Rat) - CRR2252 from Cohesion Biosciences
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shRNA set against Rat MTR (NM_030864.1) - SHH346652 from Creative biogene
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shRNA set against Rat Mtr(NM_030864.1) - SHH207379 from Creative biogene
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MTR shRNA Plasmid (Rat) - CHR2252 from Cohesion Biosciences
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MTR miRNA 3'UTR clone - MiUTR1R-04048 from Creative biogene
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