ENO1

Gene Symbol ENO1
Entrez Gene 2023
Alt Symbol ENO1L1, MPB1, NNE, PPH
Species Human
Gene Type protein-coding
Description enolase 1, (alpha)
Other Description 2-phospho-D-glycerate hydro-lyase|MYC promoter-binding protein 1|alpha enolase like 1|alpha-enolase|enolase-alpha|non-neural enolase|phosphopyruvate hydratase|plasminogen-binding protein|tau-crystallin
Swissprots Q53FT9 B2RD59 Q96GV1 Q7Z3V6 Q71V37 Q8WU71 Q16704 Q4TUS4 Q9UM55 Q9UCH6 Q9BT62 Q658M5 P22712 Q6GMP2 P06733 Q53HR3
Accessions AAY43128 CAA34360 CBN61326 EAW71604 EAW71605 P06733 AF035286 AAB88178 AK098420 AK222517 BAD96237 AK223192 BAD96912 AK298600 BAH12823 AK309177 AK309291 AK315417 BAG37806 AL833741 CAH56247 AM393606 CAL38482 BC001810 AAH01810 BC004325 AAH04325 BC004458 AAH04458 BC009218 AAH09218 BC009912 AAH09912 BC011130 AAH11130 BC015641 AAH15641 BC021166 AAH21166 BC022545 AAH22545 BC027725 AAH27725 BC050642 AAH50642 BC113034 AAI13035 BT007163 AAP35827 BX537400 CAD97642 D28437 BAA05803 DQ891441 ABM82367 DQ894619 ABM85545 EF036495 ABO65081 GU170215 ADK47995 M14328 AAA52387 M55914 AAA35698 X84907 CAA59331 XM_006710433 XP_006710496 NM_001201483 NP_001188412 NM_001428 NP_001419
Function Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10802057}. Cell membrane {ECO:0000269|PubMed:10802057}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000269|PubMed:10802057}. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line.
Tissue Specificity The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Top Pathways Glycolysis / Gluconeogenesis, RNA degradation, Biosynthesis of amino acids, Carbon metabolism

Enolase-1 (D2S1A) Rabbit mAb - 13410 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2S1A
Western blot analysis of extracts from various cell lines using Enolase-1 (D2S1A) Rabbit mAb.

Enolase-1 Antibody - 3810 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using Enolase-1 Antibody.

α Enolase (12) - sc-101514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α Enolase (12): sc-101514. Western blot analysis of human recombinant α Enolase.

α Enolase (9) - sc-101513 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α Enolase (9): sc-101513. Western blot analysis of human recombinant α Enolase.

α Enolase (28) - sc-101515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α Enolase (28): sc-101515. Western blot analysis of human recombinant α Enolase.

α Enolase (L-27) - sc-100812 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
α Enolase (L-27): sc-100812. Western blot analysis of α Enolase expression in MCF7 whole cell lysate.

Enolase (A-5) - sc-271384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Enolase (A-5): sc-271384. Western blot analysis of Enolase expression in Hep G2 whole cell lysate.

Enolase (B-8) - sc-271792 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Enolase (B-8): sc-271792. Western blot analysis of α Enolase expression in non-transfected: sc-110760 (A) and human α Enolase transfected: sc-112734 (B) 293 whole cell lysates.

Enolase (D-8) - sc-390163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Enolase (D-8): sc-390163. Western blot analysis of Enolase expression in Hep G2 (A) and HeLa (B) whole cell lysates.

Enolase (C-19) - sc-7455 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Enolase (C-19): sc-7455. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization using indirect FITC (A) staining and HeLa cells using direct Alexa Fluor 488 (B) staining.

Enolase (G-20) - sc-31857 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Enolase (G-20): sc-31857. Western blot analysis of Enolase expression in non-transfected: sc-110760 (A) and human Enolase transfected: sc-112734 (B) 293 whole cell lysates.

Enolase (H-300) - sc-15343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Enolase (H-300): sc-15343. Western blot analysis of Enolase expression in A549 whole cell lysate (A) and rat skeletal muscle tissue extract (B).

Enolase (V-15) - sc-31858 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Enolase (V-15): sc-31858. Western blot analysis of Enolase expression in non-transfected: sc-110760 (A) and human Enolase transfected: sc-112734 (B) 293 whole cell lysates.

Anti-ENO1 + ENO2 + ENO3 antibody - ab105053 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-ENO1 antibody - ab85086 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab85086, at a 1/100 dilution, staining ENO1 in the cytoplasm and membrane of formalin fixed, paraffin embedded renal tubules by Immunohistochemistry.

Anti-ENO1 antibody - ab97586 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ENO1 antibody (ab97586) at 1/3000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-ENO1 antibody [2G2AG11BF8] - ab112994 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G2AG11BF8
Immunprecipitation of ENO1 by ab112994. Staining of ENO1 (47 kDa) from HeLa cell lysate (1), Human liver (2) and Heart (3) homogenates. The identity of the protein was confirmed by mass spectrometry. This gel was stained with colloidal Coomassie blue G.

Anti-ENO1 antibody [3D9BE1] - ab195171 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9BE1

Anti-ENO1 antibody [EPR10863(B)] - ab155102 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10863(B)
All lanes : Anti-ENO1 antibody [EPR10863(B)] (ab155102) at 1/1000 dilutionLane 1 : MCF7 cell lysateLane 2 : Jurkat cell lysateLane 3 : A431 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ENO1 antibody [EPR10864(B)] - ab155955 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10864(B)
All lanes : Anti-ENO1 antibody [EPR10864(B)] (ab155955) at 1/1000 dilutionLane 1 : MCF7 cell lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLane 4 : A431 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Non Neuronal Enolase antibody - ab54979 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Non Neuronal Enolase antibody (ab54979) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human lymphoma tissue.

Anti-Non Neuronal Enolase antibody - ab35075 from Abcam

Prices $373.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-Non Neuronal Enolase antibody [8G8] - ab118866 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8G8
ab118866 at 5 µg/ml staining Non Neuronal Enolase in Paraffin-embedded Human breast tissue by immunohistochemistry.

Anti-ENO1 / Alpha Enolase Antibody - LS-C27288 from LifeSpan Bioscience

Prices $330.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal
Staining of Jurkat cells with Rabbit anti-Human NNE polyclonal antibody (LS-C27288).

Anti-ENO1 / Alpha Enolase Antibody - LS-C96066 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal
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