Gene Symbol | TFAP2D |
---|---|
Entrez Gene | 83741 |
Alt Symbol | TFAP2BL1 |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 delta (activating enhancer binding protein 2 delta) |
Other Description | AP-2 like|AP2-delta|activating enhancer binding protein 2 beta-like 1|activating enhancer-binding protein 2-delta|transcription factor AP-2 beta (activating enhancer binding protein 2 beta)-like 1|transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1|transcription factor AP-2-beta-like 1|transcription factor AP-2-delta |
Swissprots | Q7Z6R9 Q8IWX0 |
Accessions | EAX04354 Q7Z6R9 AY028376 AAK16926 BC144200 BC166653 AAI66653 DT221015 NM_172238 NP_758438 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas. {ECO:0000269|PubMed:11733187}. |
AP-2δ siRNA (h) - sc-95077 from Santa Cruz Biotechnology
|
||||||||
AP-2δ shRNA Plasmid (h) - sc-95077-SH from Santa Cruz Biotechnology
|
||||||||
AP-2δ shRNA (h) Lentiviral Particles - sc-95077-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU002421 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21247 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21247 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR00932 from Sigma-Aldrich
|
||||||||
TFAP2D siRNA (Human) - CRJ3185 from Cohesion Biosciences
|
||||||||
TFAP2D RNAi - H00083741-R01 from Novus Biologicals
|
||||||||
TFAP2D - MBS8217946 from MyBioSource
|
||||||||
shRNA set against Human TFAP2D (NM_172238.3) - SHH426104 from Creative biogene
|
||||||||
shRNA set against Human TFAP2D(NM_172238.3) - SHL066612 from Creative biogene
|
||||||||
TFAP2D shRNA Plasmid (Human) - CHJ3185 from Cohesion Biosciences
|
||||||||
TFAP2D miRNA 3'UTR clone - MiUTR1H-10338 from Creative biogene
|