| Gene Symbol |
QSOX1
|
| Entrez Gene |
5768
|
| Alt Symbol |
Q6, QSCN6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
quiescin Q6 sulfhydryl oxidase 1
|
| Other Description |
hQSOX|sulfhydryl oxidase 1
|
| Swissprots |
Q8WVP4 Q59G29 Q8TDL6 Q5T2X0 O00391
|
| Accessions |
EAW91076 EAW91077 O00391 AB209280 BAD92517 AF361868 AAM00263 AK092177 AK290842 BAF83531 AK290887 BAF83576 AY358941 AAQ89300 BC017692 AAH17692 BC100023 AAI00024 BX382719 CB137990 DQ584886 JF432792 ADZ16009 L42379 AAA89173 U97276 AAC09010 NM_001004128 NP_001004128 NM_002826 NP_002817
|
| Function |
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation. {ECO:0000269|PubMed:10542195, ECO:0000269|PubMed:10708601, ECO:0000269|PubMed:12176051, ECO:0000269|PubMed:16806532, ECO:0000269|PubMed:17331072, ECO:0000269|PubMed:18393449}.
|
| Subcellular Location |
Isoform 1: Golgi apparatus membrane; Single- pass membrane protein.
|
| Tissue Specificity |
Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. {ECO:0000269|PubMed:10708601, ECO:0000269|Ref.9}.
|
![Western Blot: Quiescin Q6 Overexpression Lysate (Adult Normal) [NBP2-10744] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Quiescin Q6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6924_Quiescin%2520Q6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10744-img0001.jpg)