IMMT

Gene Symbol IMMT
Entrez Gene 10989
Alt Symbol HMP, MINOS2, P87, P87/89, P89, PIG4, PIG52
Species Human
Gene Type protein-coding
Description inner membrane protein, mitochondrial
Other Description MICOS complex subunit MIC60|cell proliferation-inducing gene 4/52 protein|cell proliferation-inducing protein 52|mitochondrial inner membrane organizing system 2|mitochondrial inner membrane protein|mitofilin|motor protein|proliferation-inducing gene 4
Swissprots Q8TAJ5 Q14539 Q6IBL0 Q15092 Q9P0V2 Q7Z3X1 Q69HW5 Q16891 B2R5N6 Q68D41 B1H0U5
Accessions EAW99462 EAW99463 Q16891 AF148646 AAF73126 AK225780 AK296676 BAG59273 AK299014 BAG61094 AK299596 BAG61528 AK300017 BAG61832 AK304197 BAG65077 AK309004 AK312251 BAG35183 AY232292 AAP69987 AY921637 AAX10024 BC002412 AAH02412 BC005983 AAH05983 BC027458 AAH27458 BC107419 AAI07420 BU729109 BX537369 CAD97612 CR456793 CAG33074 CR749590 CAH18389 D21091 BAA04653 D21092 BAA04654 D21093 BAA04655 D21094 BAA04656 DC403234 EU831472 ACE87159 EU831559 ACE86478 L42572 AAA85336 XM_005264110 XP_005264167 XM_005264113 XP_005264170 XM_005264114 XP_005264171 XM_011532497 XP_011530799 NM_001100169 NP_001093639 NM_001100170 NP_001093640 NM_006839 NP_006830
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:0000269|PubMed:22114354}.
Subcellular Location Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Mitofilin (B-10) - sc-390706 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mitofilin (B-10): sc-390706. Western blot analysis of Mitofilin expression in Raji (A) and HeLa (B) whole cell lysates.

Mitofilin (D-3) - sc-390707 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mitofilin (D-3): sc-390707. Western blot analysis of Mitofilin expression in Raji (A) and HeLa (B) whole cell lysates.

Mitofilin (C-20) - sc-79633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Mitofilin (Y-17) - sc-79636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mitofilin (Y-17): sc-79636. Western blot analysis of Mitofilin expression in A-10 whole cell lysate.

Mitofilin (H-294) - sc-366446 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Mitofilin (H-294): sc-366446. Western blot analysis of Mitofilin expression in Hep G2 (A), HeLa (B), A-431 (C) and NCI-H460 (D) whole cell lysates and human heart tissue extract (E).

Anti-Mitofilin antibody - ab93323 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of Mitofilin using anti-Mitofilin polyclonal antibody (ab93323) shows staining in p19 Cells.

Anti-Mitofilin antibody - ab109424 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Mitofilin antibody (ab109424) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 3 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 4 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 5 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 6 : U-87 MG (Human glioblastoma astrocytoma) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Mitofilin antibody - ab182763 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human breast tissue labeling Mitofilin with ab182763 at 1/12 dilution (left panel). Right panel is treated with the immunogen.

Anti-Mitofilin antibody - ab126948 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Mitofilin antibody (ab126948) at 1/1000 dilution + U-87 MG cell lysate at 30 µg

Anti-Mitofilin antibody - ab48139 from Abcam

Prices $392.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells with ab48139 at 1/500 dilution labeling mitochondria.

Anti-Mitofilin antibody [2E4AD5] - ab110329 from Abcam

Prices $392.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4AD5
Immunocytochemistry analysis using ab110329 at 5µg/ml staining Mitofilin in Cultured Human fibroblasts. (Fixed and permeabilized) followed by a fluorescent goat-anti-mouse IgG.

Anti-Mitofilin antibody [2E4AD5] (Alexa Fluor® 488) - ab198028 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E4AD5
ab198028 staining Mitofilin in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilised in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated with ab198028 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal [DM1A] to alpha Tubulin (Alexa Fluor® 594, shown in red) at 1/167 dilution overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Mitofilin antibody [2E4AD5] (Alexa Fluor® 647) - ab198036 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E4AD5
ab198036 staining Mitofilin in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilised in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated with ab198036 at 1/50 dilution (shown in red) and ab195887, Mouse monoclonal [DM1A] to alpha Tubulin (Alexa Fluor® 488, shown in green) at 1/167 dilution overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Mitofilin antibody [2E4AD5] (HRP) - ab198037 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E4AD5
All lanes : Anti-Mitofilin antibody [2E4AD5] (HRP) (ab198037) at 1/5000 dilutionLane 1 : Human Heart Mitochondrial lysate (ab110337) at 5 µgLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate at 20 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Mitofilin antibody [EPR8749] - ab137057 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8749
All lanes : Anti-Mitofilin antibody [EPR8749] (ab137057) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Human fetal heart tissue lysateLane 3 : Human fetal muscle tissue lysateLane 4 : A673 cell lysateLane 5 : Saos 2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

Anti-IMMT / Mitofilin Antibody - LS-C332240 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human breast cancer tissue using IMMT antibody.

Anti-IMMT / Mitofilin Antibody (clone 1A8) - LS-C139360 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A8

Anti-IMMT / Mitofilin Antibody - LS-C314077 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IMMT / Mitofilin Antibody - LS-C341485 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IMMT / Mitofilin Antibody (N-Terminus) - LS-C345589 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of IMMT Antibody with human 293T Whole Cell lysate.

Anti-APP / Beta Amyloid Precursor Antibody - LS-C175832 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Amyloid beta 1-16 pAb in extracts from HeLa and Jurkat cells.

Anti-IMMT / Mitofilin Antibody (aa382-634) - LS-C178594 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IMMT / Mitofilin Antibody (aa170-203) - LS-C344333 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from A431, HeLa, HepG2, MCF-7, Raji, U-87 MG cell line (from left to right) with IMMT Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-APP / Beta Amyloid Precursor Antibody (Glu737/662) - LS-C175916 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Amyloid A4 (E737) pAb in paraffin-embedded human Brain tissue.

Anti-IMMT / Mitofilin Antibody (aa438-467) - LS-C165222 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with IMMT Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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