Gene Symbol | IMMT |
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Entrez Gene | 10989 |
Alt Symbol | HMP, MINOS2, P87, P87/89, P89, PIG4, PIG52 |
Species | Human |
Gene Type | protein-coding |
Description | inner membrane protein, mitochondrial |
Other Description | MICOS complex subunit MIC60|cell proliferation-inducing gene 4/52 protein|cell proliferation-inducing protein 52|mitochondrial inner membrane organizing system 2|mitochondrial inner membrane protein|mitofilin|motor protein|proliferation-inducing gene 4 |
Swissprots | Q8TAJ5 Q14539 Q6IBL0 Q15092 Q9P0V2 Q7Z3X1 Q69HW5 Q16891 B2R5N6 Q68D41 B1H0U5 |
Accessions | EAW99462 EAW99463 Q16891 AF148646 AAF73126 AK225780 AK296676 BAG59273 AK299014 BAG61094 AK299596 BAG61528 AK300017 BAG61832 AK304197 BAG65077 AK309004 AK312251 BAG35183 AY232292 AAP69987 AY921637 AAX10024 BC002412 AAH02412 BC005983 AAH05983 BC027458 AAH27458 BC107419 AAI07420 BU729109 BX537369 CAD97612 CR456793 CAG33074 CR749590 CAH18389 D21091 BAA04653 D21092 BAA04654 D21093 BAA04655 D21094 BAA04656 DC403234 EU831472 ACE87159 EU831559 ACE86478 L42572 AAA85336 XM_005264110 XP_005264167 XM_005264113 XP_005264170 XM_005264114 XP_005264171 XM_011532497 XP_011530799 NM_001100169 NP_001093639 NM_001100170 NP_001093640 NM_006839 NP_006830 |
Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:0000269|PubMed:22114354}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Mitofilin CRISPR/Cas9 KO Plasmid (h) - sc-403617 from Santa Cruz Biotechnology
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Mitofilin HDR Plasmid (h) - sc-403617-HDR from Santa Cruz Biotechnology
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Mitofilin Double Nickase Plasmid (h) - sc-403617-NIC from Santa Cruz Biotechnology
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Mitofilin Double Nickase Plasmid (h2) - sc-403617-NIC-2 from Santa Cruz Biotechnology
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Mitofilin CRISPR Activation Plasmid (h) - sc-403617-ACT from Santa Cruz Biotechnology
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Mitofilin CRISPR Activation Plasmid (h2) - sc-403617-ACT-2 from Santa Cruz Biotechnology
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Mitofilin Lentiviral Activation Particles (h) - sc-403617-LAC from Santa Cruz Biotechnology
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Mitofilin Lentiviral Activation Particles (h2) - sc-403617-LAC-2 from Santa Cruz Biotechnology
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Mitofilin siRNA (h) - sc-75791 from Santa Cruz Biotechnology
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Mitofilin shRNA Plasmid (h) - sc-75791-SH from Santa Cruz Biotechnology
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Mitofilin shRNA (h) Lentiviral Particles - sc-75791-V from Santa Cruz Biotechnology
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Mitofilin RNAi - H00010989-R02 from Novus Biologicals
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Mitofilin RNAi - H00010989-R03 from Novus Biologicals
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MISSION® esiRNA - EHU106691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10653 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10653 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02377 from Sigma-Aldrich
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IMMT siRNA (Human) - CRH7504 from Cohesion Biosciences
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Mitofilin RNAi - H00010989-R01 from Novus Biologicals
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IMMT - MBS8230869 from MyBioSource
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shRNA set against Human IMMT (NM_006839.2) - SHH319257 from Creative biogene
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shRNA set against Human IMMT(NM_006839.2) - SHL176808 from Creative biogene
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IMMT shRNA Plasmid (Human) - CHH7504 from Cohesion Biosciences
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IMMT miRNA 3'UTR clone - MiUTR1H-04934 from Creative biogene
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IMMT miRNA 3'UTR clone - MiUTR3H-03318 from Creative biogene
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