| Gene Symbol | Selp |
|---|---|
| Entrez Gene | 25651 |
| Alt Symbol | PSELECT |
| Species | Rat |
| Gene Type | protein-coding |
| Description | selectin P |
| Other Description | CD62 antigen-like family member P|GMP-140|LECAM3|P-selectin|PADGEM|granule membrane protein 140|leukocyte-endothelial cell adhesion molecule 3|platelet activation dependent granule-external membrane protein|selectin, platelet |
| Swissprots | P98106 |
| Accessions | EDM09362 P98106 BC101919 AAI01920 L23088 AAA60325 XM_006250150 XP_006250212 NM_013114 NP_037246 |
| Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1 (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in all tissues examined: spleen, lung, brain, liver, heart, kidney, thymus and small intestine. |
| Top Pathways | Cell adhesion molecules (CAMs), Staphylococcus aureus infection, Malaria |