NCOR1

Gene Symbol NCOR1
Entrez Gene 9611
Alt Symbol N-CoR, N-CoR1, PPP1R109, TRAC1, hN-CoR
Species Human
Gene Type protein-coding
Description nuclear receptor corepressor 1
Other Description nuclear receptor co-repressor 1|protein phosphatase 1, regulatory subunit 109|thyroid hormone- and retinoic acid receptor-associated corepressor 1
Swissprots E9PGV6 Q9UQ18 Q86YY0 B3DLF8 O75376 Q9UPV5
Accessions EAX04492 EAX04493 EAX04494 EAX04495 EAX04496 O75376 AB028450 BAA83818 AB028451 BAA83819 AB028970 BAA82999 AF044209 AAC33550 AF087856 AAP97166 AF303584 AAO32940 AF303585 AAO32941 AF303586 AAO32942 AK295893 BAG58687 AK302746 BAG63960 AK307614 AK310405 AL137641 CAB70854 AW015698 BC026028 AAH26028 BC035748 BC050594 AAH50594 BC056862 AAH56862 BC058511 AAH58511 BC068996 AAH68996 BC107772 AAI07773 BC142648 AAI42649 BC167431 AAI67431 BC172437 AAI72437 BJ995810 XM_005256866 XP_005256923 XM_005256867 XP_005256924 XM_005256868 XP_005256925 XM_005256871 XP_005256928 XM_005256872 XP_005256929 XM_005256873 XP_005256930 XM_005256874 XP_005256931 XM_005256875 XP_005256932 XM_006721601 XP_006721664 XM_006721602 XP_006721665 XM_006721603 XP_006721666 XM_006721604 XP_006721667 XM_011524083 XP_011522385 XM_011524084 XP_011522386 XM_011524085 XP_011522387 XM_011524086 XP_011522388 NM_001190438 NP_001177367 NM_001190440 NP_001177369 NM_006311 NP_006302
Function Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. {ECO:0000269|PubMed:14527417}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00624}.
Top Pathways Transcriptional misregulation in cancer

NCoR1 Antibody - 5948 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using NCoR1 Antibody.

N-CoR (C-20) - sc-1609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of N-CoR expression in K-562 whole cell lysate (A) and nuclear extract (B). Antibodies tested include N-CoR (N-19): sc-1611 (A) and N-CoR (C-20): sc-1609 (B).

N-CoR (N-19) - sc-1611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of N-CoR expression in K-562 whole cell lysate (A) and nuclear extract (B). Antibodies tested include N-CoR (N-19): sc-1611 (A) and N-CoR (C-20): sc-1609 (B).

N-CoR (H-303) - sc-8994 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
N-CoR (H-303): sc-8994. Immunofluorescence staining of methanol-fixed K-562 cells showing nuclear localization.

Anti-Nuclear Receptor Corepressor NCoR antibody - ab58396 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nuclear Receptor Corepressor NCoR antibody (ab58396) at 1/500 dilutionLane 1 : MDA-MB-435 cell extract with no immunizing peptideLane 2 : MDA-MB-435 cell extract with immunizing peptide

Anti-Nuclear Receptor Corepressor NCoR antibody - ChIP Grade - ab24552 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Nuclear Receptor Corepressor NCoR antibody - ChIP Grade (ab24552) at 1/1000 dilution + HeLa nuclear extract

Anti-Nuclear Receptor Corepressor NCoR antibody - ChIP Grade - ab3482 from Abcam

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab3482 labelling Nuclear Receptor Corepressor NCoR in the nucleus of Mouse breast tissue (right) compared with a negative control (left) by Immunohistochemistry (formalin/PFA-fixed paraffin-embedded sections). To expose target proteins, antigen retrieval method was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Tissue was blocked in 3% H2O2-methanol for 15 min at room temperature, then incubated with primary antibody (1:200 in 3% BSA-PBS) overnight at 4°C. A HRP-conjugated anti-rabbit was used as the secondary antibody, followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.

Anti-N-CoR / NCOR1 Antibody (aa1525-1575) - LS-C73194 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa1770-1947) - LS-C130982 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa1510-1540) - LS-C190118 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, AP) - LS-C279983 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, APC) - LS-C279985 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, Biotin) - LS-C279984 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, FITC) - LS-C279986 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, Azide-free, HRP) - LS-C279987 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54, PE) - LS-C279988 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, AP) - LS-C279989 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, APC) - LS-C279990 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, FITC) - LS-C279992 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, Biotin) - LS-C279991 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, Azide-free, HRP) - LS-C279993 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus, PE) - LS-C279994 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (C-Terminus) - LS-C328006 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa24-54) - LS-C328005 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-N-CoR / NCOR1 Antibody (aa51-100) - LS-C118605 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using NCoR1 Antibody. The picture on the right is treated with the synthesized peptide.
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