| Gene Symbol | BCL2A1 |
|---|---|
| Entrez Gene | 597 |
| Alt Symbol | ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | BCL2-related protein A1 |
| Other Description | bcl-2-like protein 5|bcl-2-related protein A1|bcl2-L-5|hematopoietic BCL2-related protein A1|hemopoietic-specific early response protein|protein BFL-1 |
| Swissprots | Q86W13 Q16548 Q6FGZ4 Q99524 Q6FH19 |
| Accessions | CBX47512 EAW99129 Q16548 AL110097 AY234180 AAO89009 BC016281 AAH16281 BG198875 BG204033 BG216703 BT007103 AAP35767 CD640106 CR541937 CAG46735 CR541962 CAG46760 DQ891109 ABM82035 DQ894290 ABM85216 U27467 AAC50288 U29680 AAC50438 Y09397 CAA70566 NM_001114735 NP_001108207 NM_004049 NP_004040 |
| Function | Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm. |
| Tissue Specificity | Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies. |
| Top Pathways | Transcriptional misregulation in cancer |