| Gene Symbol |
BCL2A1
|
| Entrez Gene |
597
|
| Alt Symbol |
ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCL2-related protein A1
|
| Other Description |
bcl-2-like protein 5|bcl-2-related protein A1|bcl2-L-5|hematopoietic BCL2-related protein A1|hemopoietic-specific early response protein|protein BFL-1
|
| Swissprots |
Q86W13 Q16548 Q6FGZ4 Q99524 Q6FH19
|
| Accessions |
CBX47512 EAW99129 Q16548 AL110097 AY234180 AAO89009 BC016281 AAH16281 BG198875 BG204033 BG216703 BT007103 AAP35767 CD640106 CR541937 CAG46735 CR541962 CAG46760 DQ891109 ABM82035 DQ894290 ABM85216 U27467 AAC50288 U29680 AAC50438 Y09397 CAA70566 NM_001114735 NP_001108207 NM_004049 NP_004040
|
| Function |
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
|
| Top Pathways |
Transcriptional misregulation in cancer
|
![Western Blot: Bcl2A1 Overexpression Lysate (Adult Normal) [NBP2-07920] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Bcl2A1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4346_Bcl2A1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07920-img0001.jpg)