ANLN

Gene Symbol	ANLN
Entrez Gene	54443
Alt Symbol	FSGS8, Scraps, scra
Species	Human
Gene Type	protein-coding
Description	anillin, actin binding protein
Other Description	actin-binding protein anillin
Swissprots	Q9H8Y4 Q6NSK5 Q9NVP0 Q5CZ78 Q9NVN9 Q9NQW6
Accessions	CAL40337 EAW94067 EAW94068 EAW94069 EAW94070 EAW94071 EAW94072 Q9NQW6 AF273437 AAF75796 AK001468 BAA91710 AK001472 BAA91711 AK023208 BAB14463 AK094574 AK291254 BAF83943 AK299803 BAG61678 BC034692 AAH34692 BC070066 AAH70066 BE885510 BQ434804 BU630923 CR936650 CAI56788 XM_006715746 XP_006715809 XM_006715747 XP_006715810 NM_001284301 NP_001271230 NM_001284302 NP_001271231 NM_018685 NP_061155
Function	Required for cytokinesis (PubMed:16040610). Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. May play a significant role in podocyte cell migration (PubMed:24676636). {ECO:0000269|PubMed:10931866, ECO:0000269|PubMed:12479805, ECO:0000269|PubMed:15496454, ECO:0000269|PubMed:16040610, ECO:0000269|PubMed:16357138, ECO:0000269|PubMed:24676636}.
Subcellular Location	Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody.
Tissue Specificity	Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors. {ECO:0000269|PubMed:16203764, ECO:0000269|PubMed:24676636}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Anillin full length protein - ab132001 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human Anillin peptide - ab23117 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Recombinant Human Anillin Protein - H00054443-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Anillin (C Terminus) blocking peptide - GTX89791-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Bovine

Anillin (internal) blocking peptide - GTX89306-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Anillin Peptide - AC21-0432-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ANILLIN Peptide - AC21-0953-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Anillin / ANLN - H00054443-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Anillin / ANLN - H00054443-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ANILLIN Peptide - 45-253P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ANILLIN Peptide - 45-254P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

ANLN fusion protein - ag3793 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ANLN fusion protein - ag19294 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Anillin (ANLN) - RPJ640Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Anillin (ANLN) - RPJ640Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Actin-binding protein anillin(ANLN) ,partial - CSB-YP865109HU CSB-EP865109HU CSB-BP865109HU CSB-MP865109HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Actin-binding protein anillin(ANLN) ,partial - MBS1425558 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ANILLIN/Scraps, Peptide - MBS428552 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Bovine

ANILLIN/Scraps, Peptide - MBS426751 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

Anillin Recombinant Protein Antigen - NBP2-38630PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ANLN Peptide, Human - M34GP00674H from Creative Peptides Category Peptide Source Synthetic. Species Human

Anillin Recombinant Protein Antigen - NBP2-33857PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

ANLN Immunizing peptide - orb17817 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Anillin Recombinant Protein Antigen - NBP2-52908PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E. coli Species Human

Anillin Recombinant Protein Antigen - NBP2-52907PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E. coli Species Human

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