| Gene Symbol |
F8
|
| Entrez Gene |
2157
|
| Alt Symbol |
AHF, DXS1253E, F8B, F8C, FVIII, HEMA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
coagulation factor VIII, procoagulant component
|
| Other Description |
antihemophilic factor|coagulation factor VIII|coagulation factor VIIIc|factor VIII F8B
|
| Swissprots |
Q14286 Q5HY69 P00451
|
| Accessions |
AAA52420 AAB61261 AAC32196 AAD50437 AAV85964 ABB58721 ABC25733 ABC25738 ABC25743 ABC25748 ABC25753 ABC25762 ABC25767 ABC25772 ABC25777 ABC25782 ABC25787 ABC25792 ABC25797 ABC25802 ABC25807 ABC25812 ABC25817 ABC25822 ABC25827 ABC25832 ABC25837 ABC25842 ABC25847 ABC25852 ABC25857 ABC25862 ABC25867 ABC25872 ABC25877 ABC25882 ABC25887 ABC25892 ABC25897 ABC25902 ABC25907 ABC25912 ABC25917 ABC25922 ABC25927 ABC25932 ABC25937 ABC25942 ABC25947 ABC25952 ABC25957 ABC25962 ABC25967 ABC25972 ABC25977 ABC25982 ABI26644 ABJ51912 ABJ51913 ABJ51914 ABJ51915 ABJ51916 ABJ51917 ABJ51918 ABJ51919 ABJ51920 ABJ51921 ABJ51922 ABJ51923 ABJ51924 ABJ51925 ABJ51926 ABJ51927 ABJ51928 ABJ51929 ABJ51930 ABJ55908 ABJ55909 ABJ55910 ABJ55911 ABJ55912 ABJ55913 ABK19827 ABK19828 ABK19829 ABK19830 ABK19831 ABQ51215 ACC77588 ADO65749 ADO65750 ADO65751 ADO65752 ADO65753 ADZ72842 AER23831 BAA94310 BAA94311 BAA94312 CAA25612 CAB40351 CAV28538 EAW72645 EAW72646 EAW72647 P00451 AK289947 BAF82636 AK292902 BAF85591 AK295164 BAH11996 AK307726 AK313707 BAG36452 AX746360 CAD97566 BC022513 AAH22513 BC064380 AAH64380 BC098389 AAH98389 BC111967 AAI11968 BC111969 AAI11970 BC150305 BC166700 AAI66700 BI547023 FN811132 CBL59398 JF916726 AEI17944 K01740 AAA52484 M14113 AAA52485 M90707 AAA58466 X01179 CAA25619 XM_011531126 XP_011529428 NM_000132 NP_000123 NM_019863 NP_063916
|
| Function |
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
|
| Subcellular Location |
Secreted, extracellular space.
|
| Top Pathways |
Complement and coagulation cascades
|