| Gene Symbol |
RHOQ
|
| Entrez Gene |
23433
|
| Alt Symbol |
ARHQ, HEL-S-42, RASL7A, TC10, TC10A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ras homolog family member Q
|
| Other Description |
RAS-like, family 7, member A|epididymis secretory protein Li 42|ras homolog gene family, member Q|ras-like protein TC10|ras-like protein family member 7A|rho-related GTP-binding protein RhoQ
|
| Swissprots |
D6W5A6 Q0VGN1 Q6P146 Q52LS8 Q53SJ1 P17081 Q7Z480 Q6NS39
|
| Accessions |
AAY14834 EAX00246 EAX00247 EAX00248 EAX00249 EAX00250 EAX00251 P17081 AF498976 AAM21123 AK095329 BC013135 BC033251 BC056154 AAH56154 BC065291 AAH65291 BC070485 AAH70485 BC093805 AAH93805 BC101806 AAI01807 BU928962 EU794657 ACJ13711 M31470 AAA36547 XM_005264229 XP_005264286 XM_011532726 XP_011531028 XM_011532727 XP_011531029 XM_011532728 XP_011531030 NM_012249 NP_036381
|
| Function |
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. {ECO:0000269|PubMed:15546864}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15546864}. Cell membrane {ECO:0000269|PubMed:15546864}; Lipid-anchor {ECO:0000269|PubMed:15546864}.
|
| Top Pathways |
Insulin signaling pathway
|
![Western Blot: TC10 Overexpression Lysate (Adult Normal) [NBL1-15359] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TC10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7909_TC10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15359-img0002.jpg)