Gene Symbol | RHOQ |
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Entrez Gene | 23433 |
Alt Symbol | ARHQ, HEL-S-42, RASL7A, TC10, TC10A |
Species | Human |
Gene Type | protein-coding |
Description | ras homolog family member Q |
Other Description | RAS-like, family 7, member A|epididymis secretory protein Li 42|ras homolog gene family, member Q|ras-like protein TC10|ras-like protein family member 7A|rho-related GTP-binding protein RhoQ |
Swissprots | D6W5A6 Q0VGN1 Q6P146 Q52LS8 Q53SJ1 P17081 Q7Z480 Q6NS39 |
Accessions | AAY14834 EAX00246 EAX00247 EAX00248 EAX00249 EAX00250 EAX00251 P17081 AF498976 AAM21123 AK095329 BC013135 BC033251 BC056154 AAH56154 BC065291 AAH65291 BC070485 AAH70485 BC093805 AAH93805 BC101806 AAI01807 BU928962 EU794657 ACJ13711 M31470 AAA36547 XM_005264229 XP_005264286 XM_011532726 XP_011531028 XM_011532727 XP_011531029 XM_011532728 XP_011531030 NM_012249 NP_036381 |
Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. {ECO:0000269|PubMed:15546864}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15546864}. Cell membrane {ECO:0000269|PubMed:15546864}; Lipid-anchor {ECO:0000269|PubMed:15546864}. |
Top Pathways | Insulin signaling pathway |
TC10 CRISPR/Cas9 KO Plasmid (h) - sc-416491 from Santa Cruz Biotechnology
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TC10 HDR Plasmid (h) - sc-416491-HDR from Santa Cruz Biotechnology
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TC10 Double Nickase Plasmid (h) - sc-416491-NIC from Santa Cruz Biotechnology
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TC10 Double Nickase Plasmid (h2) - sc-416491-NIC-2 from Santa Cruz Biotechnology
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TC10 CRISPR Activation Plasmid (h) - sc-416491-ACT from Santa Cruz Biotechnology
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TC10 CRISPR Activation Plasmid (h2) - sc-416491-ACT-2 from Santa Cruz Biotechnology
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TC10 Lentiviral Activation Particles (h) - sc-416491-LAC from Santa Cruz Biotechnology
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TC10 Lentiviral Activation Particles (h2) - sc-416491-LAC-2 from Santa Cruz Biotechnology
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TC10 siRNA (h) - sc-41893 from Santa Cruz Biotechnology
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TC10 shRNA Plasmid (h) - sc-41893-SH from Santa Cruz Biotechnology
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TC10 shRNA (h) Lentiviral Particles - sc-41893-V from Santa Cruz Biotechnology
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TC10 RNAi - H00023433-R01 from Novus Biologicals
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MISSION® esiRNA - EHU109651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18260 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18260 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR14147 from Sigma-Aldrich
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RHOQ siRNA (Human) - CRH8268 from Cohesion Biosciences
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RHOQ - MBS8237677 from MyBioSource
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shRNA set against Human RHOQ(NM_012249.3) - SHR181014 from Creative biogene
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Human RHOQ siRNA - orb268770 from Biorbyt
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RHOQ shRNA Plasmid (Human) - CHH8268 from Cohesion Biosciences
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RHOQ miRNA 3'UTR clone - MiUTR4H-TG07511 from Creative biogene
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