SPAM1

Gene Symbol SPAM1
Entrez Gene 6677
Alt Symbol HEL-S-96n, HYA1, HYAL1, HYAL3, HYAL5, PH-20, PH20, SPAG15
Species Human
Gene Type protein-coding
Description sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
Other Description epididymis secretory sperm binding protein Li 96n|hyal-PH20|hyaluronidase PH-20|hyaluronoglucosaminidase PH-20|sperm surface protein PH-20
Swissprots P38567 Q8TC30
Accessions AAQ96882 CBH19453 CBL54474 CBL86562 CCA64576 CCD32726 CCF70987 EAL24329 EAL24330 EAW83604 EAW83605 EAW83606 P38567 AK292229 BAF84918 AY920278 AAX13985 AY920279 AAX13986 AY920280 AAX13987 AY920281 AAX13988 BC026163 AAH26163 BI831525 DB023094 DQ891657 ABM82583 DQ894844 ABM85770 EU794686 ACJ13740 L13779 L13781 S67798 AAC60607 X84347 CAA59086 XM_011516523 XP_011514825 XM_011516524 XP_011514826 XM_011516525 XP_011514827 XM_011516526 XP_011514828 NM_001174044 NP_001167515 NM_001174045 NP_001167516 NM_001174046 NP_001167517 NM_003117 NP_003108 NM_153189 NP_694859
Function Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. {ECO:0000269|PubMed:8282124}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity Testis. {ECO:0000269|PubMed:8234258}.
Top Pathways Glycosaminoglycan degradation

SPAM1 CRISPR/Cas9 KO Plasmid (h) - sc-405880 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 HDR Plasmid (h) - sc-405880-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 Double Nickase Plasmid (h) - sc-405880-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 Double Nickase Plasmid (h2) - sc-405880-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 CRISPR Activation Plasmid (h) - sc-405880-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 CRISPR Activation Plasmid (h2) - sc-405880-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 Lentiviral Activation Particles (h) - sc-405880-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 Lentiviral Activation Particles (h2) - sc-405880-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPAM1 siRNA (h) - sc-60822 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPAM1 shRNA Plasmid (h) - sc-60822-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPAM1 shRNA (h) Lentiviral Particles - sc-60822-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPAM1 RNAi - H00006677-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU097321 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20393 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20393 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04321 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04321

SPAM1 siRNA (Human) - CRH4554 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPAM1 RNAi - H00006677-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SPAM1 - MBS8238091 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPAM1 (NM_003117.4) - SHH415912 from Creative biogene

Category siRNA
Species Reactivities Human

Human SPAM1 siRNA - orb265056 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPAM1 shRNA Plasmid (Human) - CHH4554 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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