| Gene Symbol |
ZNF516
|
| Entrez Gene |
9658
|
| Alt Symbol |
HsT287
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 516
|
| Other Description |
-
|
| Swissprots |
Q92618
|
| Accessions |
EAW66578 Q92618 BC108287 AAI08288 BC113085 BC113086 BC128041 D16475 D86975 BAA13211 XM_011526269 XP_011524571 XM_011526270 XP_011524572 XM_011526271 XP_011524573 XM_011526272 XP_011524574 XM_011526273 XP_011524575 XM_011526274 XP_011524576 XM_011526275 XP_011524577 XM_011526276 XP_011524578 XM_011526277 XP_011524579 XR_935268 NM_014643 NP_055458
|
| Function |
Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress (PubMed:23446422). {ECO:0000250|UniProtKB:Q7TSH3, ECO:0000269|PubMed:23446422}.
|
| Subcellular Location |
Nucleus {ECO:0000250|UniProtKB:Q7TSH3}.
|