| Gene Symbol |
ACOT1
|
| Entrez Gene |
641371
|
| Alt Symbol |
ACH2, CTE-1, LACH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA thioesterase 1
|
| Other Description |
CTE-I|CTE-Ib|acyl-coenzyme A thioesterase 1|inducible cytosolic acyl-coenzyme A thioester hydrolase|long chain acyl-CoA hydrolase|long chain acyl-CoA thioester hydrolase
|
| Swissprots |
Q86TX2 A1L173 Q3I5F9
|
| Accessions |
Q86TX2 AK300886 BAG62528 BC127747 AAI27748 BC127748 AAI27749 BC132889 AAI32890 BC132891 AAI32892 BC143042 AAI43043 BC144425 AAI44426 BX161396 CAD61883 DQ082754 AAZ31236 GU727640 ADU87641 XM_011537075 XP_011535377 NM_001037161 NP_001032238
|
| Function |
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16940157}.
|
| Top Pathways |
Fatty acid elongation, Biosynthesis of unsaturated fatty acids
|
![Western Blot: ACOT1 Overexpression Lysate (Adult Normal) [NBL1-07245] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ACOT1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9532_ACOT1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07245-img0002.jpg)