CDC16

Gene Symbol	CDC16
Entrez Gene	8881
Alt Symbol	ANAPC6, APC6, CUT9
Species	Human
Gene Type	protein-coding
Description	cell division cycle 16
Other Description	CDC16Hs|anaphase-promoting complex subunit 6|anaphase-promoting complex, subunit 6|cell division cycle 16 homolog|cell division cycle protein 16 homolog|cyclosome subunit 6
Swissprots	Q9Y564 Q13042 Q96AE6 Q7Z651 Q5T8C8 A2A365
Accessions	AAS94323 CCQ43240 EAX09237 EAX09238 EAX09239 EAX09240 EAX09241 EAX09242 EAX09243 EAX09244 EAX09245 Q13042 AB209850 BAD93087 AF164598 AAD45156 AK095082 AK296424 BAG59086 AK315302 BAG37707 AL540490 BC010875 AAH10875 BC017244 AAH17244 BC050575 U18291 AAC50200 XM_005266204 XP_005266261 XM_005266206 XP_005266263 XM_006719992 XP_006720055 XM_006719993 XP_006720056 XM_011534851 XP_011533153 XM_011534852 XP_011533154 XM_011534853 XP_011533155 XR_245358 XR_245359 XR_245360 XR_941424 NM_001078645 NP_001072113 NM_003903 NP_003894
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:7736578}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:7736578}. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® APC6 siRNA I - 7279 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® APC6 siRNA II - 7164 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

Cdc16 CRISPR/Cas9 KO Plasmid (h) - sc-404163 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 HDR Plasmid (h) - sc-404163-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 Double Nickase Plasmid (h) - sc-404163-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 Double Nickase Plasmid (h2) - sc-404163-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 CRISPR Activation Plasmid (h) - sc-404163-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 CRISPR Activation Plasmid (h2) - sc-404163-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 Lentiviral Activation Particles (h) - sc-404163-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 Lentiviral Activation Particles (h2) - sc-404163-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Cdc16 siRNA (h) - sc-35035 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Cdc16 shRNA Plasmid (h) - sc-35035-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Cdc16 shRNA (h) Lentiviral Particles - sc-35035-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU094241 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5771 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5771 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01858 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr01858

CDC16 siRNA (Human) - CRH5868 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CDC16 - MBS8237795 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CDC16 (NM_003903.3) - SHH259625 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CDC16(NM_001078645.1) - SHG160163 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CDC16(NM_003903.3) - SHG160217 from Creative biogene Category siRNA Species Reactivities Human

Human CDC16 siRNA - orb266370 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CDC16 shRNA Plasmid (Human) - CHH5868 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CDC16 miRNA 3'UTR clone - MiUTR1H-01927 from Creative biogene Species Reactivities Human

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