Gene Symbol | AIFM3 |
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Entrez Gene | 150209 |
Alt Symbol | AIFL |
Species | Human |
Gene Type | protein-coding |
Description | apoptosis-inducing factor, mitochondrion-associated, 3 |
Other Description | apoptosis-inducing factor 3|apoptosis-inducing factor like |
Swissprots | Q8N5E0 Q6ZT44 D3DX38 Q8N1V3 D3DX37 B7WP37 Q96NN9 |
Accessions | EAX02924 EAX02925 EAX02926 EAX02927 EAX02928 EAX02929 EAX02930 EAX02931 Q96NN9 AK055035 BAB70841 AK094844 BAC04434 AK126917 AK295581 BAH12112 AK316042 BAH14413 AY927574 AY927594 BC032485 AAH32485 BQ028401 CR456342 CAG30228 CU013053 CAK54484 CU013341 CAK54783 DA396585 DB172173 JF432230 ADZ15447 NM_001018060 NP_001018070 NM_001146288 NP_001139760 NM_144704 NP_653305 NR_027464 |
Function | Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. {ECO:0000269|PubMed:15764604}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:15764604}. Note=Does not translocate to the nucleus upon induction of apoptosis. |
Tissue Specificity | Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). {ECO:0000269|PubMed:15764604}. |
AIFL CRISPR/Cas9 KO Plasmid (h) - sc-414674 from Santa Cruz Biotechnology
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AIFL HDR Plasmid (h) - sc-414674-HDR from Santa Cruz Biotechnology
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AIFL Double Nickase Plasmid (h) - sc-414674-NIC from Santa Cruz Biotechnology
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AIFL Double Nickase Plasmid (h2) - sc-414674-NIC-2 from Santa Cruz Biotechnology
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AIFL CRISPR Activation Plasmid (h) - sc-414674-ACT from Santa Cruz Biotechnology
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AIFL CRISPR Activation Plasmid (h2) - sc-414674-ACT-2 from Santa Cruz Biotechnology
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AIFL Lentiviral Activation Particles (h) - sc-414674-LAC from Santa Cruz Biotechnology
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AIFL Lentiviral Activation Particles (h2) - sc-414674-LAC-2 from Santa Cruz Biotechnology
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AIFL siRNA (h) - sc-72467 from Santa Cruz Biotechnology
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AIFL shRNA Plasmid (h) - sc-72467-SH from Santa Cruz Biotechnology
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AIFL shRNA (h) Lentiviral Particles - sc-72467-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2984 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2984 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02015 from Sigma-Aldrich
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AIFM3 siRNA (Human) - CRJ5643 from Cohesion Biosciences
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AIFM3 - MBS8226618 from MyBioSource
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shRNA set against Human AIFM3 (NM_144704.2) - SHH233942 from Creative biogene
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AIFM3 shRNA Plasmid (Human) - CHJ5643 from Cohesion Biosciences
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AIFM3 miRNA 3'UTR clone - MiUTR3H-13539 from Creative biogene
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AIFM3 miRNA 3'UTR clone - MiUTR3H-13540 from Creative biogene
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AIFM3 miRNA 3'UTR clone - MiUTR3H-13541 from Creative biogene
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