| Gene Symbol | CALML3 |
|---|---|
| Entrez Gene | 810 |
| Alt Symbol | CLP |
| Species | Human |
| Gene Type | protein-coding |
| Description | calmodulin-like 3 |
| Other Description | caM-like protein|calmodulin-like protein 3|calmodulin-related protein NB-1 |
| Swissprots | B2R9V6 Q5SQI4 P27482 |
| Accessions | CAA31809 CAR80870 CBX84343 EAW86443 P27482 AK313934 BAG36653 BC031889 AAH31889 CU454493 DQ891776 ABM82702 DQ894960 ABM85886 DR421766 HY060230 M36707 M58026 AAA36356 NM_005185 NP_005176 |
| Function | May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates. {ECO:0000269|PubMed:11278607, ECO:0000269|PubMed:18295593}. |
| Tissue Specificity | Expressed in normal mammary, prostate, cervical, and epidermal tissues. It is greatly reduced or undetectable in transformed cells. {ECO:0000269|PubMed:2217169}. |
| Top Pathways | Estrogen signaling pathway, Rap1 signaling pathway, Alcoholism, cAMP signaling pathway, Circadian entrainment |