| Gene Symbol |
CALML3
|
| Entrez Gene |
810
|
| Alt Symbol |
CLP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calmodulin-like 3
|
| Other Description |
caM-like protein|calmodulin-like protein 3|calmodulin-related protein NB-1
|
| Swissprots |
B2R9V6 Q5SQI4 P27482
|
| Accessions |
CAA31809 CAR80870 CBX84343 EAW86443 P27482 AK313934 BAG36653 BC031889 AAH31889 CU454493 DQ891776 ABM82702 DQ894960 ABM85886 DR421766 HY060230 M36707 M58026 AAA36356 NM_005185 NP_005176
|
| Function |
May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates. {ECO:0000269|PubMed:11278607, ECO:0000269|PubMed:18295593}.
|
| Tissue Specificity |
Expressed in normal mammary, prostate, cervical, and epidermal tissues. It is greatly reduced or undetectable in transformed cells. {ECO:0000269|PubMed:2217169}.
|
| Top Pathways |
Estrogen signaling pathway, Rap1 signaling pathway, Alcoholism, cAMP signaling pathway, Circadian entrainment
|