Gene Symbol | CALML3 |
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Entrez Gene | 810 |
Alt Symbol | CLP |
Species | Human |
Gene Type | protein-coding |
Description | calmodulin-like 3 |
Other Description | caM-like protein|calmodulin-like protein 3|calmodulin-related protein NB-1 |
Swissprots | B2R9V6 Q5SQI4 P27482 |
Accessions | CAA31809 CAR80870 CBX84343 EAW86443 P27482 AK313934 BAG36653 BC031889 AAH31889 CU454493 DQ891776 ABM82702 DQ894960 ABM85886 DR421766 HY060230 M36707 M58026 AAA36356 NM_005185 NP_005176 |
Function | May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates. {ECO:0000269|PubMed:11278607, ECO:0000269|PubMed:18295593}. |
Tissue Specificity | Expressed in normal mammary, prostate, cervical, and epidermal tissues. It is greatly reduced or undetectable in transformed cells. {ECO:0000269|PubMed:2217169}. |
Top Pathways | Estrogen signaling pathway, Rap1 signaling pathway, Alcoholism, cAMP signaling pathway, Circadian entrainment |
CALML3 CRISPR/Cas9 KO Plasmid (h) - sc-400954 from Santa Cruz Biotechnology
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CALML3 HDR Plasmid (h) - sc-400954-HDR from Santa Cruz Biotechnology
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CALML3 Double Nickase Plasmid (h) - sc-400954-NIC from Santa Cruz Biotechnology
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CALML3 Double Nickase Plasmid (h2) - sc-400954-NIC-2 from Santa Cruz Biotechnology
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CALML3 CRISPR Activation Plasmid (h) - sc-400954-ACT from Santa Cruz Biotechnology
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CALML3 CRISPR Activation Plasmid (h2) - sc-400954-ACT-2 from Santa Cruz Biotechnology
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CALML3 Lentiviral Activation Particles (h) - sc-400954-LAC from Santa Cruz Biotechnology
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CALML3 Lentiviral Activation Particles (h2) - sc-400954-LAC-2 from Santa Cruz Biotechnology
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CALML3 siRNA (h) - sc-105176 from Santa Cruz Biotechnology
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CALML3 shRNA Plasmid (h) - sc-105176-SH from Santa Cruz Biotechnology
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CALML3 shRNA (h) Lentiviral Particles - sc-105176-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU135781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5303 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5303 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06249 from Sigma-Aldrich
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CALML3 siRNA (Human) - CRH0565 from Cohesion Biosciences
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CALML3 RNAi - H00000810-R01 from Novus Biologicals
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CALML3 - MBS8202808 from MyBioSource
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CALML3 CRISPR/Cas9 KO Plasmid (h2) - sc-400954-KO-2 from Santa Cruz Biotechnology
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CALML3 HDR Plasmid (h2) - sc-400954-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CALML3 (NM_005185.2) - SHH253853 from Creative biogene
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shRNA set against Human CALML3(NM_005185.2) - SHG137453 from Creative biogene
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Human CALML3 siRNA - orb261067 from Biorbyt
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CALML3 shRNA Plasmid (Human) - CHH0565 from Cohesion Biosciences
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CALML3 miRNA 3'UTR clone - MiUTR1H-01627 from Creative biogene
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