Gene Symbol |
GP1BA
|
Entrez Gene |
2811
|
Alt Symbol |
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
glycoprotein Ib (platelet), alpha polypeptide
|
Other Description |
GP-Ib alpha|antigen CD42b-alpha|platelet glycoprotein Ib alpha chain|platelet membrane glycoprotein 1b-alpha subunit
|
Swissprots |
Q8N1F3 Q16469 P07359 Q9UEK1 Q9HDC7 Q8NG39 Q14441 Q9UQS4 E7ES66
|
Accessions |
AAA52596 AAA69491 AAB22152 AAB22153 AAK71325 ABI97031 ACY72565 ADP92426 BAA12911 BAB12038 BAC10305 BAJ15417 BAJ15418 BAJ15419 BAJ15420 BAJ15421 CAM97225 EAW90393 P07359 AI357061 BC027955 AAH27955 BE463855 DQ890943 ABM81869 DQ894105 ABM85031 HY099146 J02940 AAA52595 KC120774 AGC54780 KC120775 AGC54781 KC120776 AGC54782 NM_000173 NP_000164
|
Function |
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
ECM-receptor interaction, Hematopoietic cell lineage
|