Gene Symbol | GP1BA |
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Entrez Gene | 2811 |
Alt Symbol | BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein Ib (platelet), alpha polypeptide |
Other Description | GP-Ib alpha|antigen CD42b-alpha|platelet glycoprotein Ib alpha chain|platelet membrane glycoprotein 1b-alpha subunit |
Swissprots | Q8N1F3 Q16469 P07359 Q9UEK1 Q9HDC7 Q8NG39 Q14441 Q9UQS4 E7ES66 |
Accessions | AAA52596 AAA69491 AAB22152 AAB22153 AAK71325 ABI97031 ACY72565 ADP92426 BAA12911 BAB12038 BAC10305 BAJ15417 BAJ15418 BAJ15419 BAJ15420 BAJ15421 CAM97225 EAW90393 P07359 AI357061 BC027955 AAH27955 BE463855 DQ890943 ABM81869 DQ894105 ABM85031 HY099146 J02940 AAA52595 KC120774 AGC54780 KC120775 AGC54781 KC120776 AGC54782 NM_000173 NP_000164 |
Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
CD42b CRISPR/Cas9 KO Plasmid (h) - sc-401273 from Santa Cruz Biotechnology
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CD42b HDR Plasmid (h) - sc-401273-HDR from Santa Cruz Biotechnology
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CD42b Double Nickase Plasmid (h) - sc-401273-NIC from Santa Cruz Biotechnology
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CD42b Double Nickase Plasmid (h2) - sc-401273-NIC-2 from Santa Cruz Biotechnology
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CD42b CRISPR Activation Plasmid (h) - sc-401273-ACT from Santa Cruz Biotechnology
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CD42b CRISPR Activation Plasmid (h2) - sc-401273-ACT-2 from Santa Cruz Biotechnology
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CD42b Lentiviral Activation Particles (h) - sc-401273-LAC from Santa Cruz Biotechnology
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CD42b Lentiviral Activation Particles (h2) - sc-401273-LAC-2 from Santa Cruz Biotechnology
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CD42b siRNA (h) - sc-42789 from Santa Cruz Biotechnology
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CD42b shRNA Plasmid (h) - sc-42789-SH from Santa Cruz Biotechnology
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CD42b shRNA (h) Lentiviral Particles - sc-42789-V from Santa Cruz Biotechnology
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CD42b/GPIb alpha RNAi - H00002811-R02 from Novus Biologicals
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MISSION® esiRNA - EHU150271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9494 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9494 from Sigma-Aldrich
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GP1BA siRNA (Human) - CRH1878 from Cohesion Biosciences
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GP1BA - MBS8214944 from MyBioSource
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shRNA set against Human GP1BA (NM_000173.5) - SHH305518 from Creative biogene
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Human GP1BA siRNA - orb262380 from Biorbyt
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GP1BA shRNA Plasmid (Human) - CHH1878 from Cohesion Biosciences
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GP1BA miRNA 3'UTR clone - MiUTR3H-08648 from Creative biogene
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