Gene Symbol | TDRD9 |
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Entrez Gene | 122402 |
Alt Symbol | C14orf75, HIG-1, NET54 |
Species | Human |
Gene Type | protein-coding |
Description | tudor domain containing 9 |
Other Description | hypoxia-inducible HIG-1|putative ATP-dependent RNA helicase TDRD9|tudor domain-containing protein 9 |
Swissprots | Q96AS9 Q8N9V5 A1A4S7 Q8N7T3 Q8NDG6 Q8N827 Q6ZU54 |
Accessions | Q8NDG6 AK093483 BAC04182 AK097429 BAC05047 AK097699 BAC05144 AK125978 BAC86372 AL833915 CAD38771 BC016796 AAH16796 BC033662 BC042804 BC128057 AAI28058 BG719020 BU430972 U56244 AAC25432 XM_005267309 XP_005267366 XM_006720019 XP_006720082 XM_006720020 XP_006720083 XM_011536396 XP_011534698 XM_011536397 XP_011534699 XM_011536398 XP_011534700 XM_011536399 XP_011534701 XM_011536400 XP_011534702 XM_011536401 XP_011534703 XM_011536402 XP_011534704 NM_153046 NP_694591 |
Function | Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies (By similarity). {ECO:0000250}. |
Anti-TDRD9 antibody - ab118427 from Abcam
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Anti-TDRD9 antibody - ab122441 from Abcam
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Anti-TDRD9 / HIG-1 Antibody (aa945-994) - LS-C187139 from LifeSpan Bioscience
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Anti-TDRD9 / HIG-1 Antibody (aa1071-1120) IHC-plus⢠- LS-B5623 from LifeSpan Bioscience
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TDRD9 Antibody - NBP1-57116 from Novus Biologicals
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TDRD9 Antibody - NBP1-88426 from Novus Biologicals
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TDRD9/HIG1 Polyclonal Antibody - bs-2185R from Bioss
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Anti-TDRD9 antibody produced in rabbit - HPA038120 from Sigma-Aldrich
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Anti-TDRD9 antibody produced in rabbit - SAB2106389 from Sigma-Aldrich
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TDRD9 Antibody - C-terminal region (ARP36531_P050) - ARP36531_P050 from Aviva Systems Biology
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TDRD9 antibody - middle region (ARP36532_P050) - ARP36532_P050 from Aviva Systems Biology
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TDRD9 antibody - 70R-4621 from Fitzgerald
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TDRD9 Antibody - GWB-MM412G from Genway Biotech
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Anti-TDRD9 (aa 50-150) polyclonal antibody - DPABH-08658 from Creative Diagnostics
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Anti-TDRD9 (aa 945-994) polyclonal antibody - DPABH-12921 from Creative Diagnostics
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Anti-TDRD9 (aa 887-1031) polyclonal antibody - DPABH-20743 from Creative Diagnostics
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TDRD9-Antibody-C-terminal-region-AI10994 - AI10994 from Abgent, a WuXi AppTec company
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TDRD9, Polyclonal Antibody - MBS5300607 from MyBioSource
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TDRD9 antibody - TA341629 from Acris Antibodies
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TDRD9 antibody - TA341630 from Acris Antibodies
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TDRD9 Antibody,Biotin conjugated - CSB-PA850866LD01HU from Cusabio
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TDRD9 Antibody,FITC conjugated - CSB-PA850866LC01HU from Cusabio
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TDRD9 Antibody,HRP conjugated - CSB-PA850866LB01HU from Cusabio
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TDRD9 Antibody - CSB-PA850866LA01HU from Cusabio
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TDRD9 Antibody - abx145003 from Abbexa
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