Gene Symbol |
MAGEB2
|
Entrez Gene |
4113
|
Alt Symbol |
CT3.2, DAM6, MAGE-XP-2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
melanoma antigen family B2
|
Other Description |
DSS-AHC critical interval MAGE superfamily 6|DSS/AHC critical interval MAGE superfamily 6|MAGE XP-2 antigen|MAGE-B2 antigen|cancer/testis antigen 3.2|cancer/testis antigen family 3, member 2|melanoma antigen family B, 2|melanoma-associated antigen B2
|
Swissprots |
O75860 O15479
|
Accessions |
AAB50665 AAC23617 AAD10635 EAW99047 O15479 AF015766 AAD01565 AK223081 BAD96801 AK313347 BAG36150 BC026071 AAH26071 EU176229 ABW03680 HQ447394 ADQ31880 XM_011545512 XP_011543814 NM_002364 NP_002355
|
Function |
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}.
|
Tissue Specificity |
Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types.
|