Gene Symbol | MAGEB2 |
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Entrez Gene | 4113 |
Alt Symbol | CT3.2, DAM6, MAGE-XP-2 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma antigen family B2 |
Other Description | DSS-AHC critical interval MAGE superfamily 6|DSS/AHC critical interval MAGE superfamily 6|MAGE XP-2 antigen|MAGE-B2 antigen|cancer/testis antigen 3.2|cancer/testis antigen family 3, member 2|melanoma antigen family B, 2|melanoma-associated antigen B2 |
Swissprots | O75860 O15479 |
Accessions | AAB50665 AAC23617 AAD10635 EAW99047 O15479 AF015766 AAD01565 AK223081 BAD96801 AK313347 BAG36150 BC026071 AAH26071 EU176229 ABW03680 HQ447394 ADQ31880 XM_011545512 XP_011543814 NM_002364 NP_002355 |
Function | May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}. |
Tissue Specificity | Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types. |
MAGE-B2 CRISPR/Cas9 KO Plasmid (h) - sc-408749 from Santa Cruz Biotechnology
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MAGE-B2 HDR Plasmid (h) - sc-408749-HDR from Santa Cruz Biotechnology
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MAGE-B2 Double Nickase Plasmid (h) - sc-408749-NIC from Santa Cruz Biotechnology
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MAGE-B2 Double Nickase Plasmid (h2) - sc-408749-NIC-2 from Santa Cruz Biotechnology
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MAGE-B2 CRISPR Activation Plasmid (h) - sc-408749-ACT from Santa Cruz Biotechnology
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MAGE-B2 CRISPR Activation Plasmid (h2) - sc-408749-ACT-2 from Santa Cruz Biotechnology
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MAGE-B2 Lentiviral Activation Particles (h) - sc-408749-LAC from Santa Cruz Biotechnology
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MAGE-B2 Lentiviral Activation Particles (h2) - sc-408749-LAC-2 from Santa Cruz Biotechnology
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MAGE-B2 siRNA (h) - sc-37315 from Santa Cruz Biotechnology
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MAGE-B2 shRNA Plasmid (h) - sc-37315-SH from Santa Cruz Biotechnology
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MAGE-B2 shRNA (h) Lentiviral Particles - sc-37315-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12925 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12925 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04264 from Sigma-Aldrich
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MAGEB2 siRNA (Human) - CRH2792 from Cohesion Biosciences
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shRNA set against Human MAGEB2 (NM_002364.4) - SHH336847 from Creative biogene
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Human MAGEB2 siRNA - orb263294 from Biorbyt
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MAGEB2 shRNA Plasmid (Human) - CHH2792 from Cohesion Biosciences
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MAGEB2 miRNA 3'UTR clone - MiUTR3H-02555 from Creative biogene
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