| Gene Symbol |
WNT16
|
| Entrez Gene |
51384
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 16
|
| Other Description |
protein Wnt-16|wingless-type MMTV integration site family member 16b
|
| Swissprots |
Q9UBV4 Q9Y5C0 Q2M3G1
|
| Accessions |
AAQ96872 CAI38657 EAL24346 EAL24347 EAW83556 EAW83557 Q9UBV4 AF152584 AAD38052 AF169963 AAD49351 BC104919 AAI04920 BC104945 AAI04946 EU190890 ABW69190 NM_016087 NP_057171 NM_057168 NP_476509
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas.
|
| Top Pathways |
HTLV-I infection, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, Wnt signaling pathway
|
![Western Blot: Wnt16 Overexpression Lysate (Adult Normal) [NBL1-17865] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Wnt16.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6826_Wnt16%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17865-img0002.jpg)
![Western Blot: Wnt16 Overexpression Lysate (Adult Normal) [NBL1-17864] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Wnt16.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/13114_Wnt16%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-17864-img0002.jpg)