Gene Symbol | WNT16 |
---|---|
Entrez Gene | 51384 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 16 |
Other Description | protein Wnt-16|wingless-type MMTV integration site family member 16b |
Swissprots | Q9UBV4 Q9Y5C0 Q2M3G1 |
Accessions | AAQ96872 CAI38657 EAL24346 EAL24347 EAW83556 EAW83557 Q9UBV4 AF152584 AAD38052 AF169963 AAD49351 BC104919 AAI04920 BC104945 AAI04946 EU190890 ABW69190 NM_016087 NP_057171 NM_057168 NP_476509 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas. |
Top Pathways | HTLV-I infection, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, Wnt signaling pathway |