| Gene Symbol |
DRC1
|
| Entrez Gene |
92749
|
| Alt Symbol |
C2orf39, CCDC164, CILD21
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein regulatory complex subunit 1
|
| Other Description |
coiled-coil domain containing 164|coiled-coil domain-containing protein 164|dynein regulatory complex protein 1|dynein regulatory complex subunit 1 homolog
|
| Swissprots |
Q53R91 A8K1N8 Q53TA3 Q96MC2 Q8NDI5
|
| Accessions |
AAY14647 AAY15082 EAX00688 EAX00689 Q96MC2 AK057222 BAB71385 AK289953 BAF82642 AK307094 AL833892 CAD38748 BC009488 XM_005264637 XP_005264694 XM_005264638 XP_005264695 NM_145038 NP_659475
|
| Function |
Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending. {ECO:0000269|PubMed:23354437}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}.
|