ELN

Gene Symbol ELN
Entrez Gene 2006
Alt Symbol SVAS, WBS, WS
Species Human
Gene Type protein-coding
Description elastin
Other Description tropoelastin
Swissprots O15336 Q14238 Q14233 P15502 Q7Z316 Q6P0L4 Q14235 Q7Z3F5 B3KTS6 Q9UMF5 Q14234 Q75MU5 O15337 Q6ZWJ6
Accessions AAA52379 AAB02912 AAB17544 AAB65620 AAB65621 AAC13884 AAC98393 AAC98394 AAC98395 AAC99789 AAD14921 AAS07435 ABS29265 CAA33627 CAG26527 EAW69624 EAW69625 EAW69626 EAW69627 EAW69628 EAW69629 EAW69630 EAW69631 EAW69632 EAW69633 EAW69634 EAW69635 EAW69636 P15502 AA600350 AB208942 BAD92179 AF086171 AK075494 BAC11651 AK075554 BAC11696 AK092232 BAG52500 AK094138 BAG52824 AK095990 BAG53188 AK122731 BAC85506 AK125511 BAC86188 AK129788 AK130894 AK225659 AK304845 BAG65586 AM393341 CAL38219 BC035570 BC050379 BC065566 AAH65566 BP284909 BX537939 CAD97910 BX538199 CAD98065 M24782 AAA53190 M26867 M36860 AAA52382 X52896 XM_005250187 XP_005250244 XM_005250188 XP_005250245 XM_011515868 XP_011514170 XM_011515869 XP_011514171 XM_011515870 XP_011514172 XM_011515871 XP_011514173 XM_011515872 XP_011514174 XM_011515873 XP_011514175 XM_011515874 XP_011514176 XM_011515875 XP_011514177 XM_011515876 XP_011514178 XM_011515877 XP_011514179 NM_000501 NP_000492 NM_001081752 NP_001075221 NM_001081753 NP_001075222 NM_001081754 NP_001075223 NM_001081755 NP_001075224 NM_001278912 NP_001265841 NM_001278913 NP_001265842 NM_001278914 NP_001265843 NM_001278915 NP_001265844 NM_001278916 NP_001265845 NM_001278917 NP_001265846 NM_001278918 NP_001265847 NM_001278939 NP_001265868
Function Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). {ECO:0000250|UniProtKB:P54320}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17035250}. Note=Extracellular matrix of elastic fibers. {ECO:0000269|PubMed:17035250}.
Tissue Specificity Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin. {ECO:0000269|PubMed:8812460}.
Top Pathways Protein digestion and absorption

elastin (A-8) - sc-374638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elastin (A-8): sc-374638. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

elastin (B-10) - sc-166352 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elastin (B-10): sc-166352. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

elastin (BA-4) - sc-58756 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elastin (BA-4): sc-58756. Western blot analysis of elastin expression in mouse liver tissue extract.

elastin (A-19) - sc-17580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
elastin (A-19): sc-17580. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

elastin (C-21) - sc-17581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
elastin (C-21): sc-17581. Western blot analysis of elastin expression in non-transfected: sc-117750 (A) and human elastin transfected: sc-117067 (B) whole cell lysates.

elastin (E-11) - sc-166543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elastin (E-11): sc-166543. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

elastin (F-5) - sc-166369 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elastin (F-5): sc-166369. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

elastin (H-300) - sc-25736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
elastin (H-300): sc-25736. Western blot analysis of elastin expression in non-transfected: sc-117752 (A) and truncated human elastin transfected: sc-117067 (B) 293T whole cell lysates.

Anti-alpha Elastin antibody - ab166997 from Abcam

Prices $370.00
Sizes 50 µl
Clonality Polyclonal

Anti-alpha Elastin antibody - ab134694 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-alpha Elastin antibody (ab134694) at 1/500 dilution + A549 cell extract at 30 µg

Anti-alpha Elastin antibody - ab21596 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-Elastin antibody - ab23747 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of ab23747 staining in human skin formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab23747 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Elastin antibody - ab52115 from Abcam

Prices $379.00
Sizes 50 µl
Clonality Polyclonal
IHC image of ab52115 staining in human aorta formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab52115, 5µg/ml, for 15 mins at room temperature. A goat anti-guinea pig biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Elastin antibody [BA-4] - ab9519 from Abcam

Prices $398.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone BA-4
ab9519 staining pig small intestine tissue sections by IHC-P.  Sections were fixed with Bouins and subjected to an enzymatic antigen retreival step.  The primary antibody was diluted 1/200 in a commercially available antibody diluent (replacing the blocking step) and incubated with the sample for 1 hour at 20°C.  A HRP conjugated goat anti-mouse antibody was used as the secondary.See Abreview

Anti-Tropoelastin antibody - ab21600 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Tropoelastin antibody (ab21600) at 1/500 dilution + Heart (Human) Tissue Lysate - adult normal tissue (ab29431) at 10 µgSecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Tropoelastin antibody - ab187327 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Tropoelastin antibody (ab187327) at 1/1000 dilution + HeLa total cell extract

Anti-Tropoelastin antibody [T11E3] - ab21598 from Abcam

Prices $381.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone T11E3
Immunohistochemical analysis of frozen Human ocular tissue, staining Elastin with ab21598. An AlexaFluor&reg488-conjugated anti-mouse IgG was used as the secondary antibody.

Anti-ELN / Elastin Antibody (aa266-443) - LS-C293735 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ELN / Elastin.

Anti-ELN / Elastin Antibody (aa392-645) - LS-C314242 from LifeSpan Bioscience

Prices $405.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant ELN / Elastin.

Anti-ELN / Elastin Antibody - LS-C335270 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ELN antibody.

Anti-ELN / Elastin Antibody - LS-C23006 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELN / Elastin Antibody - LS-C27192 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ELN / Elastin Antibody - LS-C65219 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-ELN / Elastin Antibody - LS-C86069 from LifeSpan Bioscience

Prices $515.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ELN / Elastin Antibody - LS-C121749 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
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