Gene Symbol | ELN |
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Entrez Gene | 2006 |
Alt Symbol | SVAS, WBS, WS |
Species | Human |
Gene Type | protein-coding |
Description | elastin |
Other Description | tropoelastin |
Swissprots | O15336 Q14238 Q14233 P15502 Q7Z316 Q6P0L4 Q14235 Q7Z3F5 B3KTS6 Q9UMF5 Q14234 Q75MU5 O15337 Q6ZWJ6 |
Accessions | AAA52379 AAB02912 AAB17544 AAB65620 AAB65621 AAC13884 AAC98393 AAC98394 AAC98395 AAC99789 AAD14921 AAS07435 ABS29265 CAA33627 CAG26527 EAW69624 EAW69625 EAW69626 EAW69627 EAW69628 EAW69629 EAW69630 EAW69631 EAW69632 EAW69633 EAW69634 EAW69635 EAW69636 P15502 AA600350 AB208942 BAD92179 AF086171 AK075494 BAC11651 AK075554 BAC11696 AK092232 BAG52500 AK094138 BAG52824 AK095990 BAG53188 AK122731 BAC85506 AK125511 BAC86188 AK129788 AK130894 AK225659 AK304845 BAG65586 AM393341 CAL38219 BC035570 BC050379 BC065566 AAH65566 BP284909 BX537939 CAD97910 BX538199 CAD98065 M24782 AAA53190 M26867 M36860 AAA52382 X52896 XM_005250187 XP_005250244 XM_005250188 XP_005250245 XM_011515868 XP_011514170 XM_011515869 XP_011514171 XM_011515870 XP_011514172 XM_011515871 XP_011514173 XM_011515872 XP_011514174 XM_011515873 XP_011514175 XM_011515874 XP_011514176 XM_011515875 XP_011514177 XM_011515876 XP_011514178 XM_011515877 XP_011514179 NM_000501 NP_000492 NM_001081752 NP_001075221 NM_001081753 NP_001075222 NM_001081754 NP_001075223 NM_001081755 NP_001075224 NM_001278912 NP_001265841 NM_001278913 NP_001265842 NM_001278914 NP_001265843 NM_001278915 NP_001265844 NM_001278916 NP_001265845 NM_001278917 NP_001265846 NM_001278918 NP_001265847 NM_001278939 NP_001265868 |
Function | Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity). {ECO:0000250|UniProtKB:P54320}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17035250}. Note=Extracellular matrix of elastic fibers. {ECO:0000269|PubMed:17035250}. |
Tissue Specificity | Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin. {ECO:0000269|PubMed:8812460}. |
Top Pathways | Protein digestion and absorption |
Cow Elastin full length protein - ab123533 from Abcam
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Human Elastin peptide - ab101300 from Abcam
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ELN-Antibody-Center-Blocking-Peptide - BP8594c from Abgent, a WuXi AppTec company
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Elastin peptide - orb72640 from Biorbyt
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Elastin Blocking Peptide - abx064148 from Abbexa
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Human Elastin Protein - abx066394 from Abbexa
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Elastin (ELN), Human - 20-7656 from ARP American Research Products
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ELN fusion protein - Ag7179 from Proteintech Group
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ELN fusion protein - ag7159 from Proteintech Group
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Recombinant Human ELN, His-tagged - ELN-12415H from Creative Biomart
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Recombinant Human ELN - ELN-202H from Creative Biomart
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Recombinant Elastin (ELN) - RPB337Hu01 from Uscn Life Science Inc.
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Recombinant Elastin (ELN) - RPB337Mu01 from Uscn Life Science Inc.
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Recombinant Elastin (ELN) - RPB337Mu02 from Uscn Life Science Inc.
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Recombinant Elastin (ELN) - RPB337Ra01 from Uscn Life Science Inc.
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ELASTIN - 02101636 from MP Biomedicals
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Elastin Blocking Peptide - CBP2954 from Cohesion Biosciences
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Recombinant Human Elastin(ELN) - CSB-YP007617HU CSB-EP007617HU CSB-BP007617HU CSB-MP007617HU from Cusabio
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Elastin (ELN) - RPU141251 from Biomatik
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Elastin Protein - abx165527 from Abbexa
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Elastin Recombinant Protein Antigen - NBP2-33805PEP from Novus Biologicals
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Elastin Recombinant Protein Antigen - NBP1-80710PEP from Novus Biologicals
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ELN Peptide, Human - M34GP04873H from Creative Peptides
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Recombinant Elastin (ELN) - RPU41251 from Biomatik
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ELN Recombinant Protein (OPCD02899) - OPCD02899 from Aviva Systems Biology
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