| Gene Symbol |
EVI5
|
| Entrez Gene |
7813
|
| Alt Symbol |
NB4S
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ecotropic viral integration site 5
|
| Other Description |
EVI-5|dJ846D11.1 (ecotropic viral integration site 5)|ecotropic viral integration site 5 protein homolog|neuroblastoma stage 4S gene protein
|
| Swissprots |
B9A6J0 Q9H1Y9 O60447 A6NKX8
|
| Accessions |
O60447 AA725529 AB209513 BAD92750 AB449875 BAH16618 AF008915 AAC16031 BC141544 AAI41545 BC156793 AAI56794 BP282704 CN334472 XM_011542099 XP_011540401 XM_011542100 XP_011540402 XM_011542101 XP_011540403 XM_011542102 XP_011540404 XM_011542103 XP_011540405 XM_011542104 XP_011540406 XM_011542105 XP_011540407 XM_011542106 XP_011540408 XM_011542107 XP_011540409 XM_011542108 XP_011540410 XM_011542109 XP_011540411 XM_011542110 XP_011540412 XM_011542111 XP_011540413 NM_001308248 NP_001295177 NM_005665 NP_005656
|
| Function |
Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis. {ECO:0000269|PubMed:16439210}.
|
| Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.
|
| Tissue Specificity |
Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal. {ECO:0000269|PubMed:16033705, ECO:0000269|PubMed:9618176}.
|
![Western Blot: EVI5 Overexpression Lysate (Adult Normal) [NBL1-10367] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EVI5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2615_EVI5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10367-img0002.jpg)