STRA6

Gene Symbol STRA6
Entrez Gene 64220
Alt Symbol MCOPCB8, MCOPS9, PP14296
Species Human
Gene Type protein-coding
Description stimulated by retinoic acid 6
Other Description retinol binding protein 4 receptor|stimulated by retinoic acid 6 homolog|stimulated by retinoic acid gene 6 homolog|stimulated by retinoic acid gene 6 protein homolog
Swissprots Q7Z3U9 Q9H9U8 Q8TB21 B7Z5M9 F5GYI8 Q9BX78 Q71RB9 Q9BX79 I3L1G8 Q6PJF8 Q7L9G1 B7Z862 D3DW54 A8K7F1
Accessions EAW99353 EAW99354 EAW99355 EAW99356 Q9BX79 AF352728 AAK30289 AF352729 AAK30290 AF370419 AAQ15255 AK022603 BAB14122 AK056125 BAG51630 AK091152 BAG52293 AK092227 BAG52498 AK291966 BAF84655 AK298921 BAH12903 AK298928 BAH12904 AK299191 BAH12965 AK302932 BAH13848 AK309676 AK310878 AY358748 AAQ89108 AY359089 AAQ89447 BC015881 AAH15881 BC025256 AAH25256 BX537413 CAD97655 CB131492 DA700543 DA746408 XM_011521883 XP_011520185 XM_011521884 XP_011520186 XM_011521885 XP_011520187 XR_931877 NM_001142617 NP_001136089 NM_001142618 NP_001136090 NM_001142619 NP_001136091 NM_001142620 NP_001136092 NM_001199040 NP_001185969 NM_001199041 NP_001185970 NM_001199042 NP_001185971 NM_022369 NP_071764
Function May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity. Increases cellular retinol uptake from the retinol-RBP complex (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Broad expression. In adult eye expressed in sclera, retina, retinal pigment epithelium, and trabecular meshwork but not in choroid and iris. {ECO:0000269|PubMed:17273977}.

Stra6 (H-43) - sc-368358 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Stra6 (N-14) - sc-138063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Stra6 (E-12) - sc-138061 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Stra6 antibody - ab73490 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Stra6 antibody (ab73490) at 1/100 dilution + HeLa cell lysate at 36 µg

Anti-Stra6 antibody - ab178536 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Stra6 antibody (ab178536) at 1/100 dilution + HeLa cell line lysate at 35 µg

Anti-Stra6 antibody - ab169600 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Stra6 antibody (ab169600) at 1 µg/mlLane 1 : Stra6 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-STRA6 Antibody (aa593-622) IHC-plus™ - LS-B9023 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-STRA6 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-STRA6 Antibody (aa187-199) - LS-C155006 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, AP) - LS-C241369 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, APC) - LS-C241370 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, Biotin) - LS-C241371 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, FITC) - LS-C241372 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, PE) - LS-C241373 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622, AP) - LS-C241374 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622, APC) - LS-C241375 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (N-Terminus) - LS-C102342 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STRA6 antibody LS-C102342 Western blot of HepG2 cell lysate.

Anti-STRA6 Antibody (aa593-622, Biotin) - LS-C241376 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622, FITC) - LS-C241377 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622, PE) - LS-C241379 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509, Azide-free, HRP) - LS-C248274 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622, Azide-free, HRP) - LS-C248275 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa593-622) - LS-C325468 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509) - LS-C330184 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRA6 Antibody (aa482-509) - LS-C158821 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Rat Stra6 Antibody western blot of rat heart tissue lysates (35 ug/lane). The Stra6 antibody detected the Stra6 protein (arrow).

STRA6 Antibody (496613) [Unconjugated] - MAB5904 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 496613
STRA6 was detected in immersion fixed Raji human Burkitt's lymphoma cell line using Mouse Anti-Human STRA6 Monoclonal Antibody (Catalog # MAB5904) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane and cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.
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