| Gene Symbol |
SCYL2
|
| Entrez Gene |
55681
|
| Alt Symbol |
CVAK104
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SCY1-like 2 (S. cerevisiae)
|
| Other Description |
SCY1-like protein 2|coated vesicle-associated kinase of 104 kDa
|
| Swissprots |
Q6P3W7 Q9P2I7 Q9NVH3 Q9H7V5 Q96ST4 A8KAB5 Q96EF4
|
| Accessions |
EAW97630 EAW97631 EAW97632 EAW97633 EAW97634 EAW97635 EAW97636 Q6P3W7 AB037781 BAA92598 AK000936 BAA91433 AK001597 BAA91778 AK024274 BAB14869 AK026160 AK027551 BAB55194 AK125091 AK292980 BAF85669 AL133044 BC011525 BC012387 AAH12387 BC063798 AAH63798 XM_005269018 XP_005269075 XM_011538559 XP_011536861 XM_011538560 XP_011536862 XM_011538561 XP_011536863 NM_017988 NP_060458
|
| Function |
Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. {ECO:0000269|PubMed:15809293, ECO:0000269|PubMed:16914521}.
|
| Subcellular Location |
Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Note=According to PubMed:15809293, plasma membrane-associated in clathrin-coated vesicles. According to PubMed:16914521, colocalizes to the trans- Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes.
|