Pla2g4a

Gene Symbol Pla2g4a
Entrez Gene 24653
Alt Symbol Pla2c, Pla2g4, cPLA2
Species Rat
Gene Type protein-coding
Description phospholipase A2, group IVA (cytosolic, calcium-dependent)
Other Description cytosolic phospholipase A2|phospholipase A2 cytosolic|phospholipase A2 group IVA
Swissprots P50393
Accessions EDM09590 P50393 BC070940 AAH70940 S77829 AAB33847 U38376 AAC21591 NM_133551 NP_598235
Function Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Translocates to membrane vesicles in a calcium-dependent fashion. {ECO:0000250}.
Tissue Specificity In brain tissue, expressed in low levels in olfactory mitral and granule cells, in hippocampal pyramidal cells and in dentate and cerebellar granule cells.
Top Pathways Choline metabolism in cancer, Ovarian steroidogenesis, Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, Glutamatergic synapse

PLA2G4A antibody - orb39196 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
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