IGHMBP2

Gene Symbol IGHMBP2
Entrez Gene 3508
Alt Symbol CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7
Species Human
Gene Type protein-coding
Description immunoglobulin mu binding protein 2
Other Description ATP-dependent helicase IGHMBP2|DNA-binding protein SMUBP-2|GF-1|cardiac transcription factor 1|glial factor 1|immunoglobulin mu-binding protein 2|zinc finger, AN1-type domain 7
Swissprots A0PJD2 P38935 Q14177 Q00443
Accessions AAA70430 EAW74729 P38935 AB208802 BAD92039 AF052128 AK091539 AK123166 AK312565 BAG35460 BC000290 AAH00290 BC015666 BC025299 AAH25299 BC041808 BC052278 BC062312 BC080519 BC105088 AAI05089 BC105090 AAI05091 BE302389 DB448398 L14754 AAA53082 M64979 AAA58611 XM_005273974 XP_005274031 XM_005273975 XP_005274032 XM_005273976 XP_005274033 XM_011544994 XP_011543296 XR_247198 XR_949903 NM_002180 NP_002171
Function 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver- type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV. {ECO:0000250, ECO:0000269|PubMed:19158098, ECO:0000269|PubMed:19299493}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19299493}. Cytoplasm {ECO:0000269|PubMed:19299493}. Cell projection, axon {ECO:0000250}. Note=Colocalizes with the translation initiation factor EIF4G2. {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined.

IGHMBP2 (N-14) - sc-168143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IGHMBP2 (S-20) - sc-168144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SMUBP2 antibody - C-terminal - ab181742 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-IGHMBP2 Antibody (C-Terminus) - LS-C153429 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IGHMBP2 Antibody (N-Terminus) - LS-C135055 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IGHMBP2 antibody LS-C135055 Western blot of Mouse Heart lysate.

SMUBP2 Polyclonal Antibody - bs-11757R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11757R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11757R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11757R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11757R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, Cy3 Conjugated - bs-11757R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, Cy5 Conjugated - bs-11757R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11757R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, Cy7 Conjugated - bs-11757R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, FITC Conjugated - bs-11757R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, Biotin Conjugated - bs-11757R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMUBP2 Polyclonal Antibody, HRP Conjugated - bs-11757R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IGHMBP2 (716-730) antibody produced in rabbit - SAB1100188 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells was separated on SDS-PAGE, blotted with Anti-IGHMBP2 (716-730) (<B>Cat. No. SAB1100188</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + IGHMBP2 immunizing peptide (human, 716-730)

Ighmbp2 antibody, N-term - GTX49085 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-Ighmbp2 antibody, N-term used in Western blot. GTX49085

Ighmbp2 antibody - 70R-8242 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

IGHMBP2 antibody - 23945-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 23945-1-AP( IGHMBP2 Antibody) at dilution of 1:50 (under 40x lens)

IGHMBP2 antibody - 23945-1-AP from Proteintech Group

Prices $279.00
Sizes con: 39 μg/150μl
Host Rabbit
Clonality Polyclonal
HL-60 cells were subjected to SDS PAGE followed by western blot with 23945-1-AP( IGHMBP2 Antibody) at dilution of 1:600

IGHMBP2, Polyclonal Antibody - MBS2518669 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

IGHMBP2 Antibody - EPP14266 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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