Gene Symbol | IGHMBP2 |
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Entrez Gene | 3508 |
Alt Symbol | CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7 |
Species | Human |
Gene Type | protein-coding |
Description | immunoglobulin mu binding protein 2 |
Other Description | ATP-dependent helicase IGHMBP2|DNA-binding protein SMUBP-2|GF-1|cardiac transcription factor 1|glial factor 1|immunoglobulin mu-binding protein 2|zinc finger, AN1-type domain 7 |
Swissprots | A0PJD2 P38935 Q14177 Q00443 |
Accessions | AAA70430 EAW74729 P38935 AB208802 BAD92039 AF052128 AK091539 AK123166 AK312565 BAG35460 BC000290 AAH00290 BC015666 BC025299 AAH25299 BC041808 BC052278 BC062312 BC080519 BC105088 AAI05089 BC105090 AAI05091 BE302389 DB448398 L14754 AAA53082 M64979 AAA58611 XM_005273974 XP_005274031 XM_005273975 XP_005274032 XM_005273976 XP_005274033 XM_011544994 XP_011543296 XR_247198 XR_949903 NM_002180 NP_002171 |
Function | 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver- type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV. {ECO:0000250, ECO:0000269|PubMed:19158098, ECO:0000269|PubMed:19299493}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19299493}. Cytoplasm {ECO:0000269|PubMed:19299493}. Cell projection, axon {ECO:0000250}. Note=Colocalizes with the translation initiation factor EIF4G2. {ECO:0000250}. |
Tissue Specificity | Expressed in all tissues examined. |
IGHMBP2 (N-14) - sc-168143 from Santa Cruz Biotechnology
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IGHMBP2 (S-20) - sc-168144 from Santa Cruz Biotechnology
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Anti-SMUBP2 antibody - C-terminal - ab181742 from Abcam
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Anti-IGHMBP2 Antibody (C-Terminus) - LS-C153429 from LifeSpan Bioscience
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Anti-IGHMBP2 Antibody (N-Terminus) - LS-C135055 from LifeSpan Bioscience
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SMUBP2 Polyclonal Antibody - bs-11757R from Bioss
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SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11757R-A350 from Bioss
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SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11757R-A488 from Bioss
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SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11757R-A555 from Bioss
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SMUBP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11757R-A647 from Bioss
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SMUBP2 Polyclonal Antibody, Cy3 Conjugated - bs-11757R-Cy3 from Bioss
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SMUBP2 Polyclonal Antibody, Cy5 Conjugated - bs-11757R-Cy5 from Bioss
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SMUBP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11757R-Cy5.5 from Bioss
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SMUBP2 Polyclonal Antibody, Cy7 Conjugated - bs-11757R-Cy7 from Bioss
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SMUBP2 Polyclonal Antibody, FITC Conjugated - bs-11757R-FITC from Bioss
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SMUBP2 Polyclonal Antibody, Biotin Conjugated - bs-11757R-Biotin from Bioss
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SMUBP2 Polyclonal Antibody, HRP Conjugated - bs-11757R-HRP from Bioss
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Anti-IGHMBP2 (716-730) antibody produced in rabbit - SAB1100188 from Sigma-Aldrich
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Ighmbp2 antibody, N-term - GTX49085 from GeneTex
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Anti -Lactogen, Placental (PL, hPL, Choriomammotropin, Chorionic Somatomammotropin A, CSA,Chorionic Somatomammotropin Hormone 1, CSH1, CS1, CSH2, CSMT, FLJ75407, SomatotropinPrecursor) - L1022-05 from USBiological Life Science
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Ighmbp2 antibody - 70R-8242 from Fitzgerald
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IGHMBP2 antibody - 23945-1-AP from Acris Antibodies
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IGHMBP2 antibody - 23945-1-AP from Proteintech Group
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IGHMBP2, Polyclonal Antibody - MBS2518669 from MyBioSource
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IGHMBP2 Antibody - EPP14266 from Elabscience
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