Tnfrsf1a

Gene Symbol	Tnfrsf1a
Entrez Gene	21937
Alt Symbol	CD120a, FPF, TNF-R, TNF-R-I, TNF-R1, TNF-R55, TNF-alphaR1, TNFAR, TNFR60, TNFRI, TNFRp55, TNFalpha-R1, Tnfr-2, Tnfr1, p55, p55-R
Species	Mouse
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1a
Other Description	TNF receptor alpha chain|TNF-RI|TNF-alpha-R1|TNFR-I|p60|tumor necrosis factor receptor 1|tumor necrosis factor receptor superfamily member 1A|tumor necrosis factor receptor type I
Swissprots	P25118
Accessions	AAA40465 EDK99828 P25118 AK154388 BAE32554 AK159989 BAE35539 AK178992 AK181159 AK181531 AK190321 AK206708 AK206824 AK207044 AK211886 AY541589 AAS48428 AY541590 AAS48429 BC004599 AAH04599 BC052675 AAH52675 BC096429 AAH96429 CK624043 L26349 AAA59361 M59377 AAA40464 M60468 AAA39751 X57796 CAA40936 X59238 CAA41922 NM_011609 NP_035739
Function	Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways	Sphingolipid signaling pathway, Herpes simplex infection, TNF signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® TNF-R1 siRNA II (Mouse Specific) - 13570 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® TNF-R1 siRNA I (Mouse Specific) - 13369 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Mouse

TNF-R1 CRISPR/Cas9 KO Plasmid (m) - sc-423442 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 HDR Plasmid (m) - sc-423442-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 Double Nickase Plasmid (m) - sc-423442-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 Double Nickase Plasmid (m2) - sc-423442-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 CRISPR Activation Plasmid (m) - sc-423442-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 CRISPR Activation Plasmid (m2) - sc-423442-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 Lentiviral Activation Particles (m) - sc-423442-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 Lentiviral Activation Particles (m2) - sc-423442-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 siRNA (m) - sc-36688 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

TNF-R1 shRNA Plasmid (m) - sc-36688-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

TNF-R1 shRNA (m) Lentiviral Particles - sc-36688-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

MISSION® esiRNA - EMU027991 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN43234 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43234 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TNFRSF1A siRNA (Mouse) - CRM4184 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

TNFRSF1A - MBS8224811 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

shRNA set against Mouse TNFRSF1A (NM_011609.4) - SHH431984 from Creative biogene Category siRNA Species Reactivities Mouse

shRNA set against Mouse Tnfrsf1a(NM_011609.4) - SHL084962 from Creative biogene Category siRNA Species Reactivities Mouse

TNF-R1 CRISPR/Cas9 KO Plasmid (m2) - sc-423442-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

TNF-R1 HDR Plasmid (m2) - sc-423442-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Mouse TNFRSF1A siRNA - orb283660 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

TNFRSF1A shRNA Plasmid (Mouse) - CHM4184 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Mouse

TNFRSF1A miRNA 3'UTR clone - MiUTR1M-11994 from Creative biogene Species Reactivities Mouse

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