| Gene Symbol |
BRK1
|
| Entrez Gene |
55845
|
| Alt Symbol |
C3orf10, HSPC300, MDS027, hHBrk1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BRICK1, SCAR/WAVE actin-nucleating complex subunit
|
| Other Description |
BRICK1, SCAR/WAVE actin-nucleating complex subunit, homolog|haematopoietic stem/progenitor cell protein 300|probable protein BRICK1|protein BRICK1
|
| Swissprots |
Q8WUW1 Q9P082 B2R5E2
|
| Accessions |
EAW64060 EAW64061 Q8WUW1 AF161418 AAF28978 AF220047 AAF67640 AK290580 BAF83269 AK312155 BAG35089 AY148219 AAN60161 AY148220 AAN60162 BC001067 AAH01067 BC007929 AAH07929 BC019303 AAH19303 BC061515 DQ892956 ABM83882 DQ896203 ABM87202 EU176410 ABW03861 NM_018462 NP_060932
|
| Function |
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. {ECO:0000269|PubMed:18560548}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Top Pathways |
Regulation of actin cytoskeleton
|