Gene Symbol | BRK1 |
---|---|
Entrez Gene | 55845 |
Alt Symbol | C3orf10, HSPC300, MDS027, hHBrk1 |
Species | Human |
Gene Type | protein-coding |
Description | BRICK1, SCAR/WAVE actin-nucleating complex subunit |
Other Description | BRICK1, SCAR/WAVE actin-nucleating complex subunit, homolog|haematopoietic stem/progenitor cell protein 300|probable protein BRICK1|protein BRICK1 |
Swissprots | Q8WUW1 Q9P082 B2R5E2 |
Accessions | EAW64060 EAW64061 Q8WUW1 AF161418 AAF28978 AF220047 AAF67640 AK290580 BAF83269 AK312155 BAG35089 AY148219 AAN60161 AY148220 AAN60162 BC001067 AAH01067 BC007929 AAH07929 BC019303 AAH19303 BC061515 DQ892956 ABM83882 DQ896203 ABM87202 EU176410 ABW03861 NM_018462 NP_060932 |
Function | Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. {ECO:0000269|PubMed:18560548}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. |
Top Pathways | Regulation of actin cytoskeleton |
HSPC300 CRISPR/Cas9 KO Plasmid (h) - sc-405410 from Santa Cruz Biotechnology
|
||||||||
HSPC300 HDR Plasmid (h) - sc-405410-HDR from Santa Cruz Biotechnology
|
||||||||
HSPC300 Double Nickase Plasmid (h) - sc-405410-NIC from Santa Cruz Biotechnology
|
||||||||
HSPC300 Double Nickase Plasmid (h2) - sc-405410-NIC-2 from Santa Cruz Biotechnology
|
||||||||
HSPC300 CRISPR Activation Plasmid (h) - sc-405410-ACT from Santa Cruz Biotechnology
|
||||||||
HSPC300 CRISPR Activation Plasmid (h2) - sc-405410-ACT-2 from Santa Cruz Biotechnology
|
||||||||
HSPC300 Lentiviral Activation Particles (h) - sc-405410-LAC from Santa Cruz Biotechnology
|
||||||||
HSPC300 Lentiviral Activation Particles (h2) - sc-405410-LAC-2 from Santa Cruz Biotechnology
|
||||||||
HSPC300 siRNA (h) - sc-78028 from Santa Cruz Biotechnology
|
||||||||
HSPC300 shRNA Plasmid (h) - sc-78028-SH from Santa Cruz Biotechnology
|
||||||||
HSPC300 shRNA (h) Lentiviral Particles - sc-78028-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU010161 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN4874 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4874 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07043 from Sigma-Aldrich
|
||||||||
BRK1 siRNA (Human) - CRJ0966 from Cohesion Biosciences
|
||||||||
BRK1 - MBS8224430 from MyBioSource
|
||||||||
shRNA set against Human Brk1 (NM_018462.4) - SHH247762 from Creative biogene
|
||||||||
shRNA set against Human C3orf10(NM_018462.4) - SHG124633 from Creative biogene
|
||||||||
Human BRK1 siRNA - orb271467 from Biorbyt
|
||||||||
BRK1 shRNA Plasmid (Human) - CHJ0966 from Cohesion Biosciences
|
||||||||
BRK1 miRNA 3'UTR clone - MiUTR1H-01375 from Creative biogene
|