Gene Symbol | PFDN5 |
---|---|
Entrez Gene | 5204 |
Alt Symbol | MM-1, MM1, PFD5 |
Species | Human |
Gene Type | protein-coding |
Description | prefoldin subunit 5 |
Other Description | c-myc binding protein|myc modulator-1 |
Swissprots | Q9C083 A8K9A8 Q99471 Q54AA8 Q9C084 |
Accessions | BAB32643 EAW96683 EAW96684 EAW96685 EAW96686 Q99471 AB055803 BAB32644 AB055804 BAB32645 AB055805 BAB32646 AK024094 AK292623 BAF85312 BC003373 BC062671 AAH62671 BE392248 BT007195 AAP35859 NM_002624 NP_002615 NM_145897 NP_665904 NM_145896 |
Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. {ECO:0000269|PubMed:9630229}. |
Subcellular Location | Isoform 3: Nucleus. |
Tissue Specificity | Highly expressed in pancreas and skeletal muscle and moderately in other tissues. |