Gene Symbol | PFDN5 |
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Entrez Gene | 5204 |
Alt Symbol | MM-1, MM1, PFD5 |
Species | Human |
Gene Type | protein-coding |
Description | prefoldin subunit 5 |
Other Description | c-myc binding protein|myc modulator-1 |
Swissprots | Q9C083 A8K9A8 Q99471 Q54AA8 Q9C084 |
Accessions | BAB32643 EAW96683 EAW96684 EAW96685 EAW96686 Q99471 AB055803 BAB32644 AB055804 BAB32645 AB055805 BAB32646 AK024094 AK292623 BAF85312 BC003373 BC062671 AAH62671 BE392248 BT007195 AAP35859 NM_002624 NP_002615 NM_145897 NP_665904 NM_145896 |
Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. {ECO:0000269|PubMed:9630229}. |
Subcellular Location | Isoform 3: Nucleus. |
Tissue Specificity | Highly expressed in pancreas and skeletal muscle and moderately in other tissues. |
prefoldin 5 CRISPR/Cas9 KO Plasmid (h) - sc-405510 from Santa Cruz Biotechnology
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prefoldin 5 HDR Plasmid (h) - sc-405510-HDR from Santa Cruz Biotechnology
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prefoldin 5 Double Nickase Plasmid (h) - sc-405510-NIC from Santa Cruz Biotechnology
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prefoldin 5 Double Nickase Plasmid (h2) - sc-405510-NIC-2 from Santa Cruz Biotechnology
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prefoldin 5 CRISPR Activation Plasmid (h) - sc-405510-ACT from Santa Cruz Biotechnology
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prefoldin 5 CRISPR Activation Plasmid (h2) - sc-405510-ACT-2 from Santa Cruz Biotechnology
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prefoldin 5 Lentiviral Activation Particles (h) - sc-405510-LAC from Santa Cruz Biotechnology
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prefoldin 5 Lentiviral Activation Particles (h2) - sc-405510-LAC-2 from Santa Cruz Biotechnology
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prefoldin 5 siRNA (h) - sc-40876 from Santa Cruz Biotechnology
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prefoldin 5 shRNA Plasmid (h) - sc-40876-SH from Santa Cruz Biotechnology
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prefoldin 5 shRNA (h) Lentiviral Particles - sc-40876-V from Santa Cruz Biotechnology
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PFDN5 RNAi - H00005204-R02 from Novus Biologicals
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PFDN5 RNAi - H00005204-R03 from Novus Biologicals
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MISSION® esiRNA - EHU223911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16652 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16652 from Sigma-Aldrich
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PFDN5 siRNA (Human) - CRH3475 from Cohesion Biosciences
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PFDN5 RNAi - H00005204-R01 from Novus Biologicals
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shRNA set against Human PFDN5(NM_145897.2) - SHR104128 from Creative biogene
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shRNA set against Human PFDN5(NM_002624.3) - SHR104358 from Creative biogene
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shRNA set against Human PFDN5(NM_145897.2) - SHR104376 from Creative biogene
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Human PFDN5 siRNA - orb263977 from Biorbyt
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PFDN5 shRNA Plasmid (Human) - CHH3475 from Cohesion Biosciences
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PFDN5 miRNA 3'UTR clone - MiUTR1H-07797 from Creative biogene
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PFDN5 miRNA 3'UTR clone - MiUTR1H-07798 from Creative biogene
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