| Gene Symbol |
PSMB2
|
| Entrez Gene |
5690
|
| Alt Symbol |
HC7-I
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) subunit, beta type, 2
|
| Other Description |
macropain subunit C7-I|multicatalytic endopeptidase complex subunit C7-1|multicatalytic endopeptidase complex subunit C7-I|proteasome beta 2 subunit|proteasome component C7-I|proteasome subunit beta type-2|proteasome subunit, beta type, 2
|
| Swissprots |
D3DPS0 P31145 Q9BWZ9 P49721
|
| Accessions |
EAX07406 EAX07407 EAX07408 P49721 AB209470 BAD92707 AI025755 AK296956 BAH12464 AK310023 AV762678 BC000268 BC101836 AAI01837 BC105126 AAI05127 BC107901 AAI07902 BM664618 BM849239 BT007137 AAP35801 CR456862 CAG33143 D26599 BAA05646 DQ893539 ABM84465 DQ896799 ABM87798 NM_001199779 NP_001186708 NM_001199780 NP_001186709 NM_002794 NP_002785
|
| Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Top Pathways |
Proteasome
|
![Western Blot: Proteasome 20S beta2 Overexpression Lysate (Adult Normal) [NBL1-14877] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Proteasome 20S beta2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7339_Proteasome%252020S%2520beta2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14877-img0002.jpg)