Gene Symbol | PSMB2 |
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Entrez Gene | 5690 |
Alt Symbol | HC7-I |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) subunit, beta type, 2 |
Other Description | macropain subunit C7-I|multicatalytic endopeptidase complex subunit C7-1|multicatalytic endopeptidase complex subunit C7-I|proteasome beta 2 subunit|proteasome component C7-I|proteasome subunit beta type-2|proteasome subunit, beta type, 2 |
Swissprots | D3DPS0 P31145 Q9BWZ9 P49721 |
Accessions | EAX07406 EAX07407 EAX07408 P49721 AB209470 BAD92707 AI025755 AK296956 BAH12464 AK310023 AV762678 BC000268 BC101836 AAI01837 BC105126 AAI05127 BC107901 AAI07902 BM664618 BM849239 BT007137 AAP35801 CR456862 CAG33143 D26599 BAA05646 DQ893539 ABM84465 DQ896799 ABM87798 NM_001199779 NP_001186708 NM_001199780 NP_001186709 NM_002794 NP_002785 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity. |
Subcellular Location | Cytoplasm. Nucleus. |
Top Pathways | Proteasome |
20S Proteasome β2 CRISPR/Cas9 KO Plasmid (h) - sc-403536 from Santa Cruz Biotechnology
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20S Proteasome β2 HDR Plasmid (h) - sc-403536-HDR from Santa Cruz Biotechnology
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20S Proteasome β2 Double Nickase Plasmid (h) - sc-403536-NIC from Santa Cruz Biotechnology
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20S Proteasome β2 Double Nickase Plasmid (h2) - sc-403536-NIC-2 from Santa Cruz Biotechnology
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20S Proteasome β2 CRISPR Activation Plasmid (h) - sc-403536-ACT from Santa Cruz Biotechnology
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20S Proteasome β2 CRISPR Activation Plasmid (h2) - sc-403536-ACT-2 from Santa Cruz Biotechnology
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20S Proteasome β2 Lentiviral Activation Particles (h) - sc-403536-LAC from Santa Cruz Biotechnology
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20S Proteasome β2 Lentiviral Activation Particles (h2) - sc-403536-LAC-2 from Santa Cruz Biotechnology
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20S Proteasome β2 siRnA (h) - sc-62866 from Santa Cruz Biotechnology
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20S Proteasome β2 shRNA Plasmid (h) - sc-62866-SH from Santa Cruz Biotechnology
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20S Proteasome β2 shRNA (h) Lentiviral Particles - sc-62866-V from Santa Cruz Biotechnology
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Proteasome 20S beta2 RNAi - H00005690-R01 from Novus Biologicals
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MISSION® esiRNA - EHU138001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17599 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17599 from Sigma-Aldrich
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PSMB2 siRNA (Human) - CRH3837 from Cohesion Biosciences
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20S Proteasome β2 CRISPR/Cas9 KO Plasmid (h2) - sc-403536-KO-2 from Santa Cruz Biotechnology
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20S Proteasome β2 HDR Plasmid (h2) - sc-403536-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human PSMB2 (NM_002794.4) - SHH385168 from Creative biogene
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Human PSMB2 siRNA - orb264339 from Biorbyt
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PSMB2 shRNA Plasmid (Human) - CHH3837 from Cohesion Biosciences
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PSMB2 miRNA 3'UTR clone - MiUTR3H-04733 from Creative biogene
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